Significance of Inflammatory response
The inflammatory response is the body's reaction to injury or infection, a complex process involving various biological mediators and immune cells. It's a defense mechanism that can lead to pathological conditions if uncontrolled. Factors like pathogens, tissue damage, and environmental pollutants can trigger it, while compounds like curcumin, vitamin C, and hyperbaric oxygen therapy may modulate it. This response is implicated in diverse conditions, from acne and arthritis to cardiovascular disease and neurological disorders.
Synonyms: Immune response, Inflammatory reaction, Inflammatory process, Immune reaction, Inflammation, Defensive response, Immunologic response
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Inflammatory response'
In Hinduism, inflammatory response is viewed as the body's reaction to injury or infection. Ayurvedic materials and formulations are used to reduce inflammation, aligning with the holistic approach to healing.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) These are the body's reactions to injury or infection, often associated with pain and swelling in osteoarthritis.[1] (2) An inflammatory response on the ocular surface is initiated by decreased tear secretion and clearance, involving soluble and cellular mediators, and this contributes to dry eye.[2] (3) This is the body's reaction to injury or infection, involving vasodilation, increased permeability, and the migration of cells to the injured site.[3] (4) Leptin has to influence on various biological mechanisms including reproduction (initiation of human puberty), the immune and this response, hematopoiesis, angiogenesis, bone formation, and wound healing.[4] (5) This was reduced in rat models using a novel Ayurvedic formulation, suggesting that this formulation has the potential to address inflammation.[5]
From: International Research Journal of Ayurveda and Yoga
(1) These secondary to the degeneration of dopaminergic neurons may also play a role in Parkinson’s disease and contribute to its pathogenesis.[6] (2) This occurs following an injury, triggering cells below the dermis to increase collagen production as part of the wound healing process.[7] (3) It is a skin reaction characterized by erythema, edema, vesiculation, oozing, crusting and lichenification.[8] (4) Allergic reactions result in this which can range from mild discomfort to grave consequences.[9] (5) By integrating vitamin C into your routine, you can support your body’s response and protect your skin from external pollutants.[10]
From: Journal of Ayurvedic and Herbal Medicine
(1) Oxidative stress induced by hyperglycaemia, impairs haemostasis and this.[11] (2) These are decreased through inhibition of cyclooxygenase 2, lipoxygenase 5 and nitric oxide synthase with curcumin.[12] (3) Inflammatory response is evoked by the metabolic activities of dermatophytes, and it is characterized by erythema, vesiculation, pustulation, micro-abscess formation, and scaling.[13] (4) A defensive mechanism triggered by damage, infection, or irritation in the body, which can lead to various diseases if it is not properly controlled, such as the inflammation targeted by the formulation.[14] (5) This refers to the body's reaction to injury or infection, with the study examining how phytol can inhibit this response by reducing cytokine production and oxidative stress.[15]
The concept of Inflammatory response in scientific sources
Inflammatory response is the body's defense against harmful stimuli, injury, or infection. It involves immune system activation, cytokine release, and can result in tissue damage.
From: International Journal of Pharmacology
(1) Externally applied glucocorticoids are widely used principally to capitalize on their ability to inhibit these responses in various tissues.[16] (2) The etiology of neonatal sepsis is marked by an increased version of this that results in single or multiorgan failure.[17] (3) To further confirmation, groups of cytokines ELISA assays were performed to support Ajwa seeds extract's an anti-inflammatory role in reducing this.[18] (4) Hydromorphone pretreatment can exert an analgesic effect, reduce the release and production of proinflammatory cytokines during pneumoperitoneum and lower this.[19] (5) A process that has received a great deal of interest in the field of medical research because inflammation and pain underlie almost every disease process.[20]
From: The Malaysian Journal of Medical Sciences
(1) Caspase-1 is engaged both in the initiation of this and in the induction of cell death in response to tissue injury.[21] (2) Obesity, a widespread phenomenon among the population with type 2 diabetes mellitus, triggers similar occurrences.[22] (3) This is the reaction of the body's tissues to injury or infection, and infection with the virus initiates alveolar injury, resulting in this.[23] (4) This is triggered by superficial injury to the gastric mucosa, and is characterized by an increase in blood flow, plasma exudation, and recruitment of leukocytes.[24] (5) Anti-inflammatory cytokines like IL-10 act by blocking the production of these cytokines secreted by monocytes or macrophages, such as IL-6, TNF-α and IL-l.[25]
From: Asian Journal of Pharmaceutics
(1) An endogenous peptide mediator of this called bradykinin has the ability to cause brief increases in blood vessel permeability that are particularly targeted to the vasculature surrounding tumors.[26] (2) Polymerase chain reaction was used to test the inflammatory response, and TQ-SLNs demonstrated anti-inflammatory properties.[27] (3) This is a biological reaction of the immune system to injury or infection, characterized by redness, swelling, pain, and heat.[28] (4) By inhibiting PDE-4, apremilast increases cAMP levels, leading to a reduction in this.[29] (5) Uyar IS, Onal S, Akpinar MB, Gonen I, Sahin V, Uguz AC, et al . Alpha lipoic acid attenuates this during extracorporeal circulation.[30]
From: South African Family Practice
(1) The late-phase or chronic inflammatory response involves cellular infiltration, which sustains tissue swelling and oedema, and further exacerbates congestion.[31] (2) The inflammatory response is a biological process that can be influenced by drugs like corticosteroids and NSAIDs, and the text describes how these medications interact with it.[32] (3) This is the body's reaction to injury or infection, and statins may alter the inflammatory response to the common cold, and it is another area where these drugs may provide some therapeutic benefits.[33] (4) Inflammatory response can be elicited by high intensity training, and may undermine the potential beneficial effect of acute anti-inflammatory responses, and patients with underlying symptoms of systemic inflammation are at risk of exaggerating pathophysiological processes.[34] (5) This is a reaction involving cellular and molecular components, including cytokines like tumor necrosis factor, interleukin 1, interleukin 6, and interleukin 17, which promote inflammation, counter-balanced by cytokines like interleukin 4 and interleukin 10.[35]
From: South African Journal of Physiotherapy
(1) This is a reaction of the body to injury, and the study considered whether deep transverse friction might initiate or enhance this response in muscle.[36] (2) These are the body's reactions to injury or infection, and they can negatively impact skeletal muscle mass in surgical and trauma ICU patients.[37] (3) This is the body's reaction to injury, specifically in the context of burn injuries, as mentioned in the provided text.[38] (4) This refers to how synovial joint structures react to trauma, both within and outside the joint, as described in the provided text.[39] (5) This describes the body's reaction to injury or infection, involving the activation of immune cells and the release of various mediators, which can lead to both localized and systemic effects.[40]
From: Onderstepoort Journal of Veterinary Research
(1) Quarter milk samples with an SCC of < 200 000 cells/mL have been regarded as an indication of an inflammatory response.[41] (2) These are the body's reactions to injury or infection, and the presence of sarcocysts in the heart may sometimes trigger these responses, as indicated in the provided text.[42] (3) Higher white blood cell counts in Babesia-infected penguins indicate an active inflammatory response to the parasite and/or a stress response, and this highlights the body's reaction to the infection.[43] (4) An inflammatory response is a systemic inflammatory response syndrome caused by marked cytokine release, which is thought to be the cause of clinical signs in babesiosis.[44] (5) The body's reaction to burn injury, which has a synergistic response with coagulation systems, and is associated with white blood cell distribution changes.[45]
From: Journal of Metabolic Health
(1) The body's reaction to injury or infection, and how CRP is an important risk factor for cardiovascular disease, is described in the provided text.[46] (2) These are the body's reactions to injury or infection, and yoga helps to improve immune function by reducing pro-inflammatory responses and cytokines.[47]
From: South African Journal of HIV Medicine
(1) The inflammatory response is the body's natural reaction to injury or infection, and involves a complex series of events, including the recruitment of immune cells, and tissue repair.[48] (2) This is the response to a previously acquired opportunistic infection that paradoxically makes the symptoms of infection worse in IRIS cases.[49]
From: Journal of Public Health in Africa
(1) Penetrations of the female sand flea into the skin of the host induce inflammatory response due to release of metabolically active substances (proteolytic enzymes) and continuous enlargement of the parasites.[50]
From: Journal of Medicinal Plants for Economic Development
(1) These are the body's reactions to infections, which involve the activation of enzymes like lipoxygenases.[51]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Inflammatory responses are compared following soccer, basketball, volleyball, and handball games at an elite competitive level, revealing differences between sports.[52] (2) These are bodily reactions to injury or infection, and these are triggered by oxidative stress and poor quality diets, potentially increasing the risk of cardiovascular morbidity and mortality.[53] (3) The biological effects of individual-level PM(2.5) exposure on systemic immunity and "inflammatory response" in traffic policemen are investigated by Zhao, J. et al.[54] (4) It is the body's reaction to injury or infection, involving the activation of the immune system and the release of molecules that promote healing and defense.[55] (5) A protective mechanism initiated by the immune system in response to injury or infection, but chronic or dysregulated inflammation can contribute to various health problems, and the inflammatory response can be affected by factors such as childhood adversity and gut microbiota composition.[56]
From: International Journal of Pharmacology
(1) These are intricately associated with the pathophysiology of septic shock, and glucocorticoids have been demonstrated to efficaciously inhibit excessive reactions, widely employed in the clinical management of patients with septic shock.[57] (2) This refers to the body's reaction to injury or infection, and the SOX9 elevation has been reported to limit this in the IVD tissue.[58] (3) The text supports the hypothesis that COX-1 is not associated with these, but rather functions in homeostasis, as stated in the discussion.[59]
From: Sustainability Journal (MDPI)
(1) The nanoparticles stimulate "inflammatory responses" in cells, which eventually leads to genotoxicity and cytotoxicity, as shown in the text.[60] (2) α -Phellandrene, a cyclic monoterpene, attenuates inflammatory response through neutrophil migration inhibition and mast cell degranulation Life Sci 2016 , 160 , 27–33.[61] (3) Curcumin inhibits inflammatory response and bone loss during experimental periodontitis in rats, according to Zhou, Chen, Li, Sun, Song, and Wang.[62]
From: International Journal of Pharmacology
(1) The body's complex reaction to harmful stimuli, involving immune cells and molecular mediators to eliminate the initial cause of cell injury.[63] (2) Inflammatory responses induced by obesity can be inhibited by zingerone, which acts by suppressing macrophage accumulation and activation in adipose tissue.[64] (3) The body's reaction to harmful stimuli, which may be enhanced in GDM patients and is associated with the downregulation of PPAR-gamma.[65] (4) A key feature of renal Ischemia/Reperfusion injury in hyperlipidemic rats, involving the infiltration of inflammatory cells.[66] (5) The inflammatory response is a defence mechanism triggered by stimuli, involving macrophages that produce inflammatory cytokines after polarization, and can be promoted by compounds like NPPB.[67]