Significance of In vivo studies
In vivo studies, across Ayurveda, Science, and Health Sciences, involve experiments conducted within living organisms. These studies assess the effects of various substances, including herbal drugs, treatments, and formulations. They are crucial for understanding efficacy, safety, and pharmacological profiles. In vivo research utilizes animal models or clinical trials to confirm findings, identify potential side effects, and evaluate therapeutic potential in real biological systems.
Synonyms: In vivo research, Biological studies, Physiological studies
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'In vivo studies'
In Hinduism, *in vivo* studies involve research within living organisms, like animals or humans. They assess the effects, efficacy, and safety of substances like herbal drugs, aiming to confirm properties and gather crucial data for disease treatments and product commercialization.
From: Journal of Ayurvedic and Herbal Medicine
(1) These are studies conducted in living organisms, which are needed to confirm the scavenging property of the fruit before it is commercialized.[1] (2) These studies are performed within a living organism to assess the effects of herbal drugs, providing crucial data for understanding their efficacy and safety, and are used to obtain confirmatory results.[2]
From: Journal of Ayurveda and Integrated Medical Sciences
(1) These are experiments conducted in living organisms, such as animals or humans, to assess the effects of drugs or other substances.[3] (2) Research conducted within living organisms, which could be performed to further assess the efficacy of Barbari in treating diseases caused by microbes.[4] (3) These are studies conducted within a living organism, and they may be considered in the future based on the positive outcomes of Rajat Sindoor.[5] (4) These are studies that have established the antioxidant potential of components of Ayush-64, and are a part of the research process.[6] (5) These are studies conducted within a living organism, like animals, to assess the anticancer properties of Calotropis procera.[7]
The concept of In vivo studies in scientific sources
From: Onderstepoort Journal of Veterinary Research
(1) In vivo studies are experiments conducted in living organisms, which are needed to support the potential use of bee venom as a local antifungal drug, assessing its effectiveness and safety in a biological system.[8] (2) The studies of toxicity are conducted on living chickens, where the birds are orally dosed with decoctions of several concentrations over a period of time.[9]
From: International Journal of Pharmacology
(1) These experiments were conducted using albino Wistar rats, and pharmacokinetic parameters were calculated.[10] (2) The results obtained should be confirmed by these types of studies to validate the findings.[11] (3) These are studies conducted in living organisms to understand mechanisms.[12]
From: Asian Journal of Pharmaceutics
(1) PHB based ER tablet comprised 56 mg of IF and the plasma concentrations were acquired within 48 h.[13] (2) Studies are performed on animals to study the drug kinetics and therapeutic effectiveness.[14] (3) These are investigations conducted within a living organism, like an animal.[15]
From: The Malaysian Journal of Medical Sciences
(1) Studies that are necessary to investigate the effects of Zamzam water on experimental animals with induced cancers, according to the conclusion of the study.[16] (2) This is where the potential of new vaccine candidates are evaluated, as demonstrated by proteoliposomes from M. smegmatis.[17] (3) (R)-(−)-carvone was emulsified in 2% Tween 20 for in vivo studies, showing the method used for administration.[18]
From: International Journal of Pharmacology
(1) In vivo studies were conducted on mice to determine the propulsive gut motility, specifically the intestinal transit time of charcoal movement.[19] (2) Research conducted within a whole, living organism, such as animal models or human clinical trials.[20] (3) Experiments conducted on living organisms, used to assess the laxative and antidiarrheal effects of the plant.[21]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) In vivo studies are the specific types of research included in this systematic review, requiring the investigation of permanent maxillary first molars within living subjects utilizing cone-beam computed tomography technology.[22] (2) Essential types of investigations conducted within living organisms, often involving rodents like rats and mice, which are commonly utilized for researching the system that balances sugar and insulin.[23] (3) These are experiments conducted on living organisms, necessary to corroborate the findings and complete the research for developing potential food supplements.[24]
From: Sustainability Journal (MDPI)
(1) In-vivo studies have demonstrated that pulmonary contact with iron oxide nanoparticles can lead to genotoxicity and inflammation, indicating the value of in-vivo studies in understanding health risks.[25]