Significance of Immunomodulatory activity
Immunomodulatory activity, as described across Ayurveda, Science, and Health Sciences, is the capacity of a substance to modify or regulate the immune system. This involves influencing immune responses, either enhancing or suppressing them, to restore balance and improve health. This activity is found in various herbs, formulations, and compounds, potentially aiding in fighting infections, managing diseases, and enhancing the body's defense mechanisms. The ability to modulate the immune system is a key factor in the therapeutic potential of these substances.
Synonyms: Immunomodulating effect, Immune response modulation, Immune system regulation, Immune modulation effect, Immune modulation, Immune regulation, Immune system modulation
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Immunomodulatory activity'
In Hinduism, immunomodulatory activity involves substances, particularly herbal remedies, that regulate the immune system. This includes plants like A. racemosus, Pippali, and Giloy, and is seen as beneficial for various health conditions. The activity involves stimulating or suppressing immune responses to restore balance and combat diseases.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Triphala demonstrates immunomodulatory activity on neutrophil functions, indicating its capacity to influence the activity of immune cells.[1] (2) Immunomodulatory activity is present in drugs like Kutki, Kiratatikata, Rasona, Guduchi, Haritaki, Aamalaki, Rajakoshataki, Pippali, Sharapunkha, and Sariva according to the document.[2] (3) An alcoholic extract of Tribulus terrestris increased the humoral antibody titre and delayed-type hypersensitivity response, indicating this effect.[3] (4) Immunomodulatory activity is a property of T. cordifolia, believed to have Rasayana, Balya, Vayahsthapan, Ayushyaprada, Vrishya, and Chakshushya properties in Ayurveda.[4] (5) This is the capacity of the plant to modulate the immune system, as shown by studies on its effects on immune cells and responses.[5]
From: International Research Journal of Ayurveda and Yoga
(1) Immunomodulatory Activity of Swarna Prashana in Charle’s Foster Albino Rats, associated with Khedekar S, published in J Ayu Med Sci | 2016.[6] (2) T. cordifolia is said to possess the following Ayurvedic properties: Rasayana (rejuvenating), Balya, Vayahsthapan (anti-aging).[7] (3) The alcoholic and aqueous extracts of T. cordifolia have been tested successful for this activity.[8] (4) It is an effect observed with Jwaramurari Rasa, shown in tests such as phagocytosis, candidacidal assay, neutrophil locomotion chemotaxis, and NBT.[9] (5) Triphala, a combination of Terminalia chebula Retz, Terminalia belerica Roxb. and Embelica officinalis Gaertn, exhibits this on neutrophil functions.[10]
From: Journal of Ayurvedic and Herbal Medicine
(1) This refers to the capability of certain herbs, like Shunthi, to modulate the immune system's response, which is beneficial in treating conditions.[11] (2) This refers to the ability of certain herbs and formulations to modulate the immune system, which is beneficial in managing the symptoms and progression of COVID-19 and are used in compound formulations of rasayan.[12] (3) It reveals that the plant has some kind of immunomodulatory activity in the body.[13] (4) Shilajatu has been reported to reduce macrophage and lymphocyte activation and migration, as a part of its immunomodulatory activity.[14] (5) This refers to the capacity of a substance to modulate the immune system's response, which is examined in the context of one of the studies referenced in the text.[15]
The concept of Immunomodulatory activity in scientific sources
Immunomodulatory activity describes a substance's ability to regulate or modify the immune system. This includes enhancing or suppressing immune function, as demonstrated by various substances like herbal extracts, impacting the body's defense against infections and diseases by altering immune responses.
From: International Journal of Pharmacology
(1) This activity is primarily responsible for compounds like 11-hydroxymustakone, N-methyl-2 pyrrolidone, N-formylannonain, and cordifolioside.[16] (2) Carbon clearance assay-Group I (Control) mice received 2% acacia gum, orally, Group II animals received Levamisole (Khandelwal Labs) in a dose of 25 mg kg -1, orally.[17] (3) T. arjuna bark powder significantly increased the anti-SRBC antibody titre in the secondary phase of immune response.[18] (4) Immunomodulatory activity can be screened in Hibiscus rosa sinensis Linn. and ethanolic extract of Cleome gynandra Linn., according to the text.[19] (5) Further in depth study on the parameters investigated in the present experimentation need to be designed and explored for this.[20]
From: Asian Journal of Pharmaceutics
(1) The ability of substances, such as P. corylifolia seed extract, to influence and regulate the immune system's response.[21] (2) This refers to a study about the immunomodulatory activity of alcoholic extract of Rubia cordifolia Linn.[22] (3) Almost all contents of this powder more or less exhibit anti-inflammatory, antioxidant activity, and immunomodulatory activity.[23] (4) Tinospora cordifolia has been explored for its use in viral infections as an agent with both immunomodulatory and antiviral properties.[24]
From: Journal of Medicinal Plants for Economic Development
(1) This refers to the plant's ability to affect the immune system, indicating its potential in enhancing the body's defense mechanisms.[25] (2) This is assumed to be a result of the combination of phenolic compounds and the numerous coumarins found in P. sidoides.[26]
From: International Journal of Pharmacology
(1) Aloe vera has the capacity to modulate or influence the immune system.[27] (2) The capacity of a substance to influence or regulate the immune system, assessed in scientific studies using plant extracts.[28] (3) The capacity of a substance to alter or regulate the immune system's response, as observed with scorpion venom on T lymphocytes.[29] (4) This refers to the ability of a substance to modify or regulate immune responses, a property being investigated for rolipram.[30]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Mesenchymal stem cells show strong activity. MSCs conduct paracrine secretory activities, which allow MSCs to induce pleiotropic e ff ects, especially local immunomodulation.[31]