Significance of Immunomodulatory Action
Immunomodulatory Action, as described across various contexts, refers to the ability of substances, treatments, or drugs to modify or regulate the immune system. This includes enhancing immune responsiveness against pathogens, as seen in Rasayana therapies, and the ability to modulate immune responses. It also encompasses the capacity to influence the components and functions of the immune system, which can involve both enhancing and suppressing immune responses. Numerous Ayurvedic drugs and herbs, such as Pippali, Ashwagandha, and Tinospora cordifolia, exhibit these actions, contributing to the body's defense mechanisms and overall healing.
Synonyms: Immune-modulating effect, Immune regulation, Immune response modulation, Immunoregulation, Immunostimulatory action, Immune-modulating activity, Immune system regulation, Immunomodulation
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Immunomodulatory Action'
In Hinduism, Immunomodulatory Action involves substances affecting the immune system, both innate and adaptive. This includes the properties of Guduchi, Ghrita, and other herbs like Punarnavashtak Kwatha and Bhringaraja. These actions enhance immune response, promote healing, and are often associated with Rasayana and Balya actions.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) This is a proven effect of many ingredient drugs like Pippali, Sunti, Sariba, Musali, etc., used in Prakarayoga, and these drugs have actions like Krimighna (antimicrobial, antihelminthic), Jwaraghna (antipyretic), Hridya (cardioprotective), Ruchya (taste stimulant), Anulomana (laxative), and Vishaghna (antitoxic).[1] (2) This is an action of Bhringaraja, which is shown by increasing phagocytosis.[2] (3) This refers to the effect of a Ghrita prepared in a specific way, which has the ability to modulate the immune system, and is achieved through a unique formulation of Ashwagandha Ghrita with specific ingredients.[3] (4) The effect of the aqueous extract of Teramnus labialis, which was found to be statistically significant in the experimental model.[4] (5) Immunomodulatory action of Rasayana Dravyas is a process where substances specifically or non-specifically affect any immune system component or function, including the innate and adaptive arms of the immune response.[5]
The concept of Immunomodulatory Action in scientific sources
Immunomodulatory action describes a substance's ability to modify the immune system's function, enhancing or suppressing responses. This action is seen in various drugs, treatments, and substances, including those used in Ayurvedic medicine, affecting the body's defense mechanisms and potentially aiding in managing infections, inflammation, and various health conditions.
From: International Journal of Pharmacology
(1) The influence on the immune system observed in Withania somnifera and Zingiber zerumbet.[6]
From: International Journal of Pharmacology
(1) Immunomodulatory actions refer to the ability of glucocorticoids to regulate the immune system, contributing to the inhibition of tissue damage caused by ischemia/reperfusion.[7]