Significance of Immunohistochemical Staining
Immunohistochemical staining is a crucial laboratory technique used to visualize and identify specific proteins within tissue sections. This method employs antibodies to highlight the presence and distribution of various markers, such as interleukin-8, ISL1, and LHX5, thereby assisting in the diagnosis of tumors like ATRT and clear cell carcinoma. Additionally, it facilitates research by revealing protein localization in cellular processes, making it essential for tumor classification and understanding tissue-specific characteristics.
Synonyms: Immunostaining, Immunofluorescence, Histochemical staining
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The concept of Immunohistochemical Staining in scientific sources
Immunohistochemical Staining is a laboratory technique that visualizes specific proteins in tissue sections, aiding in the identification and distribution of markers like interleukin-8 and diagnosing tumors by using specific antibodies.
(1) This is a technique used to identify the presence of specific proteins in the tumor cells, helping to confirm the diagnosis of clear cell carcinoma.[1] (2) A technique used to identify specific proteins in the tumor cells, which was positive for Epithelial Membrane Antigen (EMA) and S-100 protein, and negative for Glial Fibrillary Acidic Protein (GFAP).[2] (3) This is a technique used to detect specific proteins in tissue samples, performed for p16 INK4a in this study.[3] (4) This is a technique used to detect and visualize specific proteins in tissue samples, and this method was used to determine the expression of ISL1 and LHX5.[4] (5) A laboratory technique used to identify specific proteins in tissue samples, which demonstrates myofibroblastomas being positive for markers such as CD34 and vimentin.[5]