Significance of Immune complexes
Immune complexes are structures formed from the binding of antigens to antibodies, which can lead to various health issues, including tissue damage and inflammation. They play a significant role in autoimmune diseases and are implicated in conditions like systemic lupus erythematosus and Stevens-Johnson syndrome. Elevated levels of immune complexes have been associated with disease activity and complications, highlighting their importance in understanding immune responses and potential vascular injuries during infections or autoimmune reactions.
Synonyms: Antigen-antibody complexes
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Immune complexes in scientific sources
Immune complexes are formed from the binding of antigens and antibodies, potentially causing tissue damage and inflammation, especially when they accumulate in blood vessels, according to regional sources.
From: The Malaysian Journal of Medical Sciences
(1) These are combinations of antibodies and antigens, and increased levels of these have been observed in women with the disease, suggesting a maladaptation.[1] (2) These are formed when antibodies bind to antigens, and sIgA helps to eliminate these complexes.[2] (3) A process that has been well recognised in KD and could be the source of mediating vascular injury by triggering inflammatory reactions through the activation of Fc-γ receptor or complement.[3] (4) Clusters formed by antibodies bound to antigens, their clearance is relevant to the disease activity in systemic lupus erythematosus.[4]