Significance of Hypersensitivity reaction
Hypersensitivity reaction refers to exaggerated immune responses that occur when the immune system overreacts to typically harmless substances, leading to adverse effects like rashes, hives, or severe complications. These reactions can be triggered by various allergens and medications, such as NSAIDs and sulfonamide antibiotics. Monitoring for hypersensitivity is essential, especially with drugs like abacavir and phenytoin, to prevent potential harm. Overall, hypersensitivity reactions necessitate careful management and avoidance of rechallenging after an occurrence to ensure patient safety.
Synonyms: Allergic reaction, Immune response, Hypersensitivity response, Anaphylactic reaction, Exaggerated immune response, Allergy, Sensitization, Intolerance, Hypersensitivity
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Hypersensitivity reaction'
In Hinduism, hypersensitivity reactions are seen as adverse immune responses, often triggered by substances like NSAIDs. Lavanga is viewed as a safer alternative, avoiding these negative responses.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) These are adverse immune responses, like those that can occur with NSAIDs, and Lavanga is considered a safer alternative because it does not trigger these.[1]
The concept of Hypersensitivity reaction in scientific sources
Hypersensitivity reactions are exaggerated immune responses to stimuli, causing adverse effects like allergies and severe reactions such as anaphylaxis. They can be triggered by various allergens and medications, necessitating prompt recognition and treatment.
From: South African Journal of HIV Medicine
(1) This refers to adverse reactions, often allergic, which must be monitored for when using Nevirapine.[2] (2) This is a side-effect of concern with abacavir, which inexperienced doctors may miss, leading to potential harm.[3] (3) These are immune system responses that occur after exposure to a substance, and the text describes how these reactions to abacavir were successfully managed in the ARROW trial.[4] (4) This is a condition where the body overreacts to a substance, and the text advises to watch for it and avoid rechallenging after an occurrence.[5] (5) Hypersensitivity reaction is a systemic reaction that can occur with certain medications, such as abacavir, and the guidelines provide guidance on how to recognize and manage these reactions, including the need to discontinue the drug and never re-introduce it.[6]
From: The Malaysian Journal of Medical Sciences
(1) These are allergic reactions that can occur, and participants were monitored for these.[7] (2) These are allergic reactions that can occur as a result of anti-asparaginase antibodies, leading to clinical manifestations of varying degrees or subclinical hypersensitivity.[8] (3) Reactions of the immune system classified as allergic, including symptoms like urticaria and anaphylaxis, triggered by allergens.[9] (4) An exaggerated immune response to a harmless substance, leading to allergic reactions and potential tissue damage.[10]
From: South African Family Practice
(1) These are exaggerated immune responses to substances, often resulting in allergic reactions that may require medical intervention.[11] (2) These are delayed-type reactions triggered by drugs and sometimes by infections, resulting in significant morbidity and characterized by widespread epidermal necrosis of the skin and mucosa, with potential for severe complications.[12] (3) An immune response that is exaggerated and harmful to the body, which can manifest as anaphylaxis during the perioperative period and requires prompt recognition and treatment.[13] (4) DPP-4 inhibitors are contraindicated when there is a history of a serious hypersensitivity reaction to DPP-4 inhibitors.[14]
From: International Journal of Pharmacology
(1) An exaggerated immune response to a substance that is typically harmless.[15] (2) The use of gadolinium-based contrast agents and beta-blockers together increases the risk of these.[16]
From: Journal of Public Health in Africa
(1) Hypersensitivity reactions are a consequence of the release of inflammatory mediators during mast cell degranulation, causing a range of adverse effects in individuals with allergies.[17]
From: South African Journal of Psychiatry
(1) Discontinue treatment promptly if patients experience these during treatment, and symptoms may persist after discontinuation, as mentioned in the text.[18]