Significance of Hyperplasia
Hyperplasia, fundamentally, is an increase in cell number within a tissue or organ. Science attributes it to inhibited apoptosis or factors like tumor necrosis factor. Health sciences note its role in epidermal nevi formation, bile duct changes, and adipocyte proliferation leading to obesity, potentially triggered by obesogens. Hyperplasia can also indicate a tissue's response to injury or stress, highlighting its diverse causes and implications across different biological contexts.
Synonyms: Cell proliferation, Excessive growth, Abnormal growth, Overgrowth, Proliferation, Enlargement, Expansion, Increase
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Hyperplasia in scientific sources
Hyperplasia is an increase in cell number within a tissue or organ. It can be triggered by factors like TNF-α, injury, stress, obesogens, or inhibited apoptosis, leading to conditions like epidermal nevi or obesity.
From: International Journal of Pharmacology
(1) An increase in the number of cells in a tissue or organ, observed in bile duct epithelial cells.[1] (2) An increase in the number of cells, specifically referring to the proliferation of adipocytes, which can be stimulated by obesogens and contribute to obesity.[2]
From: International Journal of Pharmacology
(1) An increase in the number of cells, potentially caused by substances like tumor necrosis factor (TNF-α).[3] (2) An increase in cell number that can result from the inhibition of apoptosis.[4]