Significance of Hydroxyl radical
Hydroxyl radicals are highly reactive oxygen species that are frequently mentioned across multiple disciplines. They are known for causing significant damage to cellular components like DNA, lipids, and proteins, leading to oxidative stress and potential cell injury. Their scavenging activity is often measured as an indicator of antioxidant properties. Hydroxyl radicals are implicated in various health concerns, including tissue damage, liver diseases, and oxidative stress.
Synonyms: Oh radical, Hydroxyl
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Hydroxyl radical'
In Hinduism, Hydroxyl radical is linked to cellular damage caused by highly reactive molecules. Certain plant extracts like Triphala, possess antioxidant properties, scavenging these harmful radicals. It is also connected to methods for determining reaction rates, offering a way to measure the activity of these radicals.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) These are highly reactive radicals that cause cellular damage, and Triphala has been shown to scavenge these, contributing to its antioxidant effects.[1] (2) The hydroxyl radicals are highly reactive and can cause harm to tissues, and catalase helps protect against these radicals in the experiment.[2] (3) The text mentions the scavenging of hydroxyl radicals, which are highly reactive molecules that can cause cellular damage, highlighting the antioxidant properties of certain plant extracts.[3]
From: Journal of Ayurvedic and Herbal Medicine
(1) These are highly reactive oxygen species that can cause damage to cells, and the scavenging activity of the extract against these radicals was also measured.[4] (2) This term is associated with a method used for determining rate constants for reactions, as described in Analysis Biochemistry in 1987, providing a way to measure the activity of these specific radicals.[5]
The concept of Hydroxyl radical in scientific sources
Hydroxyl radical is a highly reactive oxygen species (ROS) causing cellular damage. It's generated through various processes like metabolism and the Fenton reaction, contributing to oxidative stress, cell injury, and lipid peroxidation. Antioxidants are crucial for scavenging this toxic radical, protecting against damage to DNA, proteins, and lipids.
From: International Journal of Pharmacology
(1) CAT is a hemoprotein which catalyses the reduction of hydrogen peroxides and protects the tissues from highly reactive hydroxyl radicals.[6] (2) Cells treated with WNO demonstrated reduced levels of these, indicating that the extract possesses radical scavenging activity.[7] (3) It is an element of reactive oxygen species, also known as OH, as described in the text.[8] (4) A serum level measured by enzyme-linked immunosorbent assay after the patient’s venous blood was centrifuged.[9] (5) This is a free radical generated as a result of oxidation, linked with several chronic health diseases.[10]
From: Asian Journal of Pharmaceutics
(1) It is a type of reactive oxygen intermediate that is an oxygen free radical.[11] (2) It is a radical formed in the Huber-Weiss reaction, possessing the highest activity among the active forms of oxygen.[12] (3) Dismutation of superoxide anion can produce hydrogen peroxide that may be reduced to this oxidant.[13] (4) This can be scavenged by coumarins.[14] (5) CAT protects higher tissues from these highly reactive molecules by reducing hydrogen peroxides.[15]
From: The Malaysian Journal of Medical Sciences
(1) This radical is the most damaging oxygen free radical species, and can initiate the lipid peroxidation phenomenon.[16] (2) This is a component of ROS, which acts as an important mediator in multiple cell signalling pathways and immune response, produced naturally within biological systems.[17] (3) These are a type of reactive oxygen species (ROS) that can inflict oxidative damage on lipids, proteins and nucleic acids.[18] (4) Hydroxyl radicals are quenched by ∞-lipoic acid and dihydrolipoic acid (DHLA), indicating their antioxidant capabilities.[19]
From: Sustainability Journal (MDPI)
(1) Hydroxyl radicals (HO) are produced in the presence of H 2 O and OH- (electron donor species), acting as strong oxidizing agents with the potential to degrade water pollutants.[20] (2) Hydroxyl radicals initiate the oxidation of VOC in the atmosphere, typically starting with the abstraction of a hydrogen atom, forming water and an alkyl radical.[21] (3) These and holes were the predominant species in the degradation performance of MB and CIP, respectively, as determined using scavengers.[22] (4) Hydroxyl radicals are highly reactive intermediates generated by advanced oxidation processes, which degrade surfactants and contribute to the high performance in treating CWW.[23] (5) Hydroxyl radicals are free radicals that are generated through different processes, including ozonation, Fenton-based reactions, electrochemical oxidation, and ultrasound cavitation.[24]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Excess n-butanol can scavenge all the hydroxyl radicals produced (both surface-bound • OH and free • OH), whereas excess KI prefers to react with surface-bound • OH.[25] (2) Hydroxyl radical plays a major role during the removal process of tetracycline antibiotics when using the iron-loaded granular activated carbon catalyst, according to the study.[26] (3) Highly reactive and damaging molecules formed in the presence of ferrous iron, playing a significant role in numerous diseases.[27] (4) The remaining h+ at the VB potential of La-N-TiO2 can oxidize water into "hydroxyl radicals" (·OH), owing to their potential being higher than the H2O/·OH potential.[28] (5) Hydroxyl radicals, denoted as •OH, are highly reactive species that can oxidize and degrade pollutants, contributing to the overall photocatalytic degradation efficiency.[29]
From: International Journal of Pharmacology
(1) Hydroxyl radical is listed as one of the principal Reactive Oxygen Species that contributes to cell injury.[30] (2) A highly reactive type of oxygen species that can damage cells, and whose scavenging is an indicator of antioxidant activity.[31] (3) Hydroxyl radicals are reactive species whose levels can be decreased by edaravone, contributing to its antioxidant effects.[32] (4) A highly reactive molecule that damages biomolecules, produced with the involvement of iron.[33] (5) A highly reactive form of oxygen that can cause significant damage to cells and tissues.[34]
From: South African Journal of Psychiatry
(1) This is a dangerous radical generated by the Fenton reaction, but 6-OHM can quench it.[35]