Significance of High-pressure liquid chromatography
High-pressure liquid chromatography (HPLC) is an essential analytical technique in chemistry, primarily utilized for the detection, separation, and quantification of drugs in laboratory and pharmaceutical settings. This powerful method enhances the resolution and identification of impurities in pharmaceutical compounds by utilizing high pressure to improve interactions with stationary phases. HPLC plays a crucial role in various applications, including drug analysis, bioactive compound separation, and the evaluation of formulation compatibility, making it a cornerstone in pharmaceutical research and quality assessment.
Synonyms: Hplc, Liquid chromatography, High-performance liquid chromatography, Chromatographic separation, Analytical technique
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of High-pressure liquid chromatography in scientific sources
High-pressure liquid chromatography (HPLC) is an analytical technique essential for separating, identifying, and quantifying components in mixtures, playing a crucial role in various scientific and industrial applications.
From: Asian Journal of Pharmaceutics
(1) This is used to analyze drug content in accelerated temperature stability studies. It is used as stability indicating method.[1] (2) It is a technique used to identify and quantify components in the extract, injecting P. ostreatus aqueous extract and fructose standard with a mobile phase of acetonitrile and water.[2] (3) A technique used to assess the chemical degradation of gliclazide microcapsules.[3] (4) An analytical technique used in the analysis of tinidazole, alongside other methods like thin layer chromatography.[4] (5) A vital qualitative and quantitative method frequently used for quality control.[5]
From: African Journal of Primary Health Care and Family Medicine
(1) This is a specific analytical technique utilized for the examination of stavudine samples, providing precise measurements and analysis capabilities for the study.[6]
From: Sustainability Journal (MDPI)
(1) A technique used to determine organic acids and ethanol concentrations, utilizing an LC 25 Chromatography Oven and a UVD 340 U detector.[7] (2) High-pressure liquid chromatography, or HPLC, is a technique used to separate and analyze the chemical components of biochar and bio-oil, which is relevant for asphalt modification.[8]