Significance of Glibenclamide
Glibenclamide, according to the provided texts, is a multifaceted drug primarily used in diabetes treatment. It is often a standard or reference drug in studies, serving as a positive control to compare the effectiveness of new treatments. Glibenclamide is an oral medication, frequently categorized as a sulfonylurea, which stimulates insulin release from the pancreas. It's also noted for its blood glucose-lowering effects, making it a common tool in managing diabetes.
Synonyms: Glyburide, Insulin secretagogue, Oral hypoglycemic agent, Daonil
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Glibenclamide'
In Hinduism, Glibenclamide, a standard drug, serves as a reference in studies. It's orally administered to rats for 21 days, showing effects on lipid profiles. It lowers TGL, cholesterol, and LDL while raising HDL compared to diabetic controls.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Glibenclamide is a standard drug used in the study to compare its effects with Vangasindhoora, administered orally to a group of rats, and used for 21 days.[1] (2) Glibenclamide is a compound that treated animals also reduced TGL, total cholesterol, LDL, and increased HDL compared to diabetic control group.[2]
From: Journal of Ayurvedic and Herbal Medicine
(1) This was received by the positive control group, and the extract's effects were compared to it.[3]
The concept of Glibenclamide in scientific sources
Glibenclamide is a standard oral medication primarily used to treat type 2 diabetes by stimulating insulin release. It serves as a reference drug in numerous studies, comparing its blood glucose-lowering effects against new treatments and plant extracts, and is often used as a positive control.
From: International Journal of Pharmacology
(1) This was purchased from Sigma (St. Louis, MO, USA), and used as a control drug in the experiment.[4] (2) This compound (10 μM) is a KATP inhibitor, used to identify the types of K + channels involved in TMF-induced vasorelaxation.[5] (3) It is a standard drug used as a treatment and comparison in the study of streptozotocin-induced diabetic activity in rats.[6] (4) A drug used as a positive control in the study, administered to a group of diabetic rats.[7] (5) This, as well as extracts, have a considerable anti-hyperglycemic effect in rats that were given serum glucose.[8]
From: Asian Journal of Pharmaceutics
(1) A drug that uses Precirol Compritol.[9] (2) An antidiabetic drug that shows the minimum price in the regulated market.[10] (3) This is a sulphonylurea-type anti-diabetic medication with chemical similarities to repaglinide.[11] (4) A medication that has been formulated into transdermal systems and wafers for sustained therapeutic delivery.[12] (5) A standard antidiabetic drug used for treatment comparison in the study, stimulates pancreatic beta cells.[13]
From: The Malaysian Journal of Medical Sciences
(1) This medication might ameliorate oxidative stress in the kidneys of diabetic rats to a certain extent, and administration of this and metformin, and repaglinide exhibited a significant reduction in MDA concentration.[14] (2) A standard diabetic drug used in the study that improved body weight and hormonal levels in diabetic mice.[15] (3) A reference drug used in the study to compare the hypoglycaemic effects of Persea americana extracts.[16]
From: South African Family Practice
(1) This is another specific sulphonylurea medication, and its use is discouraged in the SEMDSA guidelines, especially in patients with renal impairment.[17] (2) This medication is a sulphonylurea and is recognized in the article, and its usage may vary depending on specific patient conditions and guidelines.[18]
From: Journal of Medicinal Plants for Economic Development
(1) This term is the name of a drug mentioned in the text, with a novel mechanism of action related to its effects.[19]
From: Journal of Metabolic Health
(1) The standard drug used as a positive control in the study, demonstrating the effectiveness of a known antidiabetic medication.[20]
From: International Journal of Pharmacology
(1) A standard antidiabetic drug used as a reference in studies to compare its effectiveness with new treatments.[21] (2) An established anti-diabetic drug that exhibits hypoglycemic effects.[22] (3) A standard antidiabetic drug used for comparison in studies evaluating new treatments, known for its significant blood glucose-lowering effects in diabetic patients.[23] (4) This diabetes drug influences the activity of paraoxonase 1 and platelet-activating factor acetylohydrolase, suggesting broader metabolic effects.[24] (5) A standard drug used as a reference in the study, obtained from Himedia Laboratory Limited for comparison.[25]
From: International Journal of Pharmacology
(1) A drug used in combination with Aloe vera L. juice for the treatment of diabetes mellitus patients.[26]