Significance of Gene expression
Gene expression, as defined across various scientific disciplines, is the fundamental process by which information from a gene is used to synthesize a functional gene product, typically a protein or RNA. This process is highly regulated and can be influenced by a multitude of factors, including lifestyle, environmental conditions, and various compounds. Alterations in gene expression are crucial in understanding biological processes, disease mechanisms, and the effects of interventions like medicinal herbs or specific practices.
Synonyms: Gene activity, Gene regulation, Gene transcription, Gene activation
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Gene expression'
In Hinduism, gene expression is a biological process linked to overall well-being and influenced by various factors. It is connected to the Ayurvedic cycle, metabolism, and practices like Sudarshan Kriya Yoga, impacting health through antioxidants and cellular processes.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Gene expression and cell behaviour are affected by epigenetic changes, which, unlike mutational changes, do not alter the genetic code.[1] (2) This biological process was studied in breast cancer cells after treatment with a specific extract derived from Tribulus terrestris to understand the effects.[2] (3) This is something that exogenous antioxidant molecules are capable of modulating to improve oxidative stress, according to the provided text.[3] (4) This is the process that toxicogenomics utilizes to measure and analyze to identify specific genes or patterns that can serve as biomarkers of toxicity.[4] (5) This refers to the process by which the information encoded in a gene is used to synthesize a functional gene product, which has been examined in studies on yoga.[5]
From: International Research Journal of Ayurveda and Yoga
(1) Influenced by yoga, with the potential involvement of molecular pathways, such as the NGF pathway incorporating TNF- α and IL-6, has been suggested in oral cancer.[6] (2) This is affected by yoga and meditation, and studies have looked into the effect of yoga-based intervention programs on changes in peripheral blood mononuclear cells.[7] (3) Yoga training improves the leukocytes cell survival-related gene expression in breast cancer survivors.[8] (4) High CBD extracts down-regulates ACE 2 which is the gateway to SARS ‐ CoV 2 entry into host cells.[9] (5) A process where yoga training combined with high-dose vitamin D significantly increased p53 expression in patients who had completed chemotherapy and radiotherapy.[10]
From: Journal of Ayurvedic and Herbal Medicine
(1) Micro RNAs regulate this by binding to complementary mRNAs and causing their degradation, and curcumin decreases miR-21 and increases PTEN expression, leading to decreased PI 3 K/Akt pathway activity.[11] (2) This is a function that is affected by the ayurvedic or circadian cycle, along with metabolism and other functions, indicating its immense role on overall well-being, such as the liver.[12] (3) This refers to the process of genes being used to make proteins, and dietary polyphenols have implications in neurons cellular processes, like this, apart from anti-carcinogenic and anti-atherogenic implications.[13]
The concept of Gene expression in scientific sources
Gene expression, the core concept, is the process of using a gene's information to synthesize a functional product, most often a protein. The provided text explores this process in various contexts, including its influence by environmental factors, disease, treatments, and cellular processes, utilizing techniques like PCR.
From: International Journal of Pharmacology
(1) The process by which information from a gene is used in the synthesis of a functional gene product, which can be altered by plant extracts to affect cell migration.[14] (2) Gene expression is relevant, as the gene expression of SREBP-1 α, SREBP-2, PPAR α and LPL regulates lipid metabolism, so it has a close relationship with obesity.[15] (3) The process by which information from a gene is used to synthesize a functional gene product, such as a protein, which can be altered by various factors including oxidative stress.[16]
From: The Malaysian Journal of Medical Sciences
(1) Gene expression of e-selectin, monocyte-endothelial cell interaction, and endothelial activation are reduced by saffron and its bioactive compound, crocin, as demonstrated in in vitro studies.[17] (2) This can be enhanced through genetic modification of host cells, such as with CERT and XBP1s, which has proven to be a promising strategy to eliminate or reduce the bottlenecks in recombinant protein expression, particularly folding and secretion.[18] (3) The process by which information from a gene is used in the synthesis of a functional gene product. The extract can disturb this.[19]
From: Asian Journal of Pharmaceutics
(1) This is the process by which the information encoded in a gene is used to synthesize a functional gene product.[20] (2) This is altered by curcumin and its derivatives in the adipocyte differentiation process.[21] (3) Future work will be done to establish the influence that HL 1 may have on the expression of CSF-1 R, including studies of this.[22]
From: Onderstepoort Journal of Veterinary Research
(1) This is the process by which the information in a gene is used to create a product, and it is measured in the experiment.[23] (2) This is the process by which information from a gene is used in the synthesis of a functional gene product, and it is of fundamental importance in biomedical research.[24] (3) This is the process by which the information in a gene is used to create a functional product, and the study investigates the gene expression of NSP 4 and VP 7.[25]
From: South African Journal of HIV Medicine
(1) The process by which information from a gene is used to synthesize a functional gene product, such as a protein, and this process can be affected by medications, potentially influencing metabolic processes and weight.[26]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product, and this study examined its changes related to mitochondrial function.[27] (2) Gene expression is influenced by the AS 3 MT haplotype and DNA methylation, providing insights into the molecular mechanisms of arsenic metabolism.[28] (3) This was altered in human skin fibroblasts subsequent to exposure to GSM cellular phone radiofrequency.[29]
From: Sustainability Journal (MDPI)
(1) The process by which information from a gene is used in the synthesis of a functional gene product, regulated by quorum sensing signaling molecules.[30] (2) Gene expression patterns are altered by salt stress, affecting various physiological processes.[31] (3) Gene expression during heterocyst differentiation is a topic of detailed biological research, exploring the molecular mechanisms that govern the formation of specialized cells in certain microorganisms.[32]
From: International Journal of Pharmacology
(1) This refers to the expression of genes, such as aldose reductase, which is studied to understand the impact of treatments on the enzyme's activity.[33]
From: International Journal of Pharmacology
(1) The process by which information from a gene is used in the synthesis of a functional gene product, often a protein.[34] (2) Gene expression refers to the levels of specific genes, such as Sox9, Col2a1, aggrecan, and Col10a1, which were assessed in BMSCs using RT-PCR.[35] (3) The process by which information from a gene is used in the synthesis of a functional gene product, such as a protein.[36]
From: South African Journal of Psychiatry
(1) This is a continuous trait that may be included as aspects when defining phenotypes for mapping studies in genetics.[37] (2) This refers to the process by which genes are activated to produce proteins, and the study analyzes these changes in fear extinction.[38]
From: Religions Journal (MDPI)
(1) "Gene Expression" is examined in relation to maternal care and the transmission of individual differences in stress reactivity across generations, revealing epigenetic mechanisms.[39]