Significance of Fracture risk
Fracture risk is the probability of experiencing a bone fracture. It is influenced by factors like bone density, microarchitecture, age, and underlying health conditions, such as osteoporosis. Low bone mineral density, osteopenia, and weakened bones increase this risk. Healthcare providers assess fracture risk to determine the need for treatment and prevention strategies. It is a critical outcome in clinical trials and a central focus of osteoporosis management.
Synonyms: Bone fracture risk, Fracture probability, Osteoporosis risk, Bone fragility, Fracture susceptibility
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Fracture risk in scientific sources
From: South African Family Practice
(1) Bone mineral density (BMD) is the most quantifiable predictor of fracture risk for those who have not yet suffered a fragility fracture, according to the provided text.[1] (2) This is the likelihood of experiencing a bone break, and lower vitamin K intake is a predictor of this, and should be considered.[2] (3) This term refers to the likelihood of experiencing a fracture, which is a key outcome measured in clinical trials evaluating the effectiveness of osteoporosis treatments, such as those using ibandronate.[3]
From: International Journal of Pharmacology
(1) Various studies reported on the effect of glucocorticoids on this in rheumatoid arthritis patients but no clear consensus about the magnitude of risk could be finalized.[4] (2) The inverse association between this and statin use was uncovered many years ago in some observational studies.[5] (3) Fracture risk is the likelihood of experiencing a bone fracture, which is elevated in individuals with osteoporosis.[6]
From: Asian Journal of Pharmaceutics
(1) It can be increased when bones become weak and fragile, usually occurring in the spine, wrist, and hips, but can affect other bones.[7] (2) The likelihood of breaking a bone, which is increased in individuals with osteoporosis due to decreased bone density. The study evaluates guidelines for assessing this.[8] (3) Bone turnover markers are providing information on this independent of bone mineral density.[9]
From: South African Journal of HIV Medicine
(1) The results of this study may inform strategies to prevent these in postmenopausal women living with HIV, which is a major concern.[10] (2) This describes the possibility of experiencing a bone break, a concern that is related to bone health in individuals with human immunodeficiency virus.[11]
From: The Malaysian Journal of Medical Sciences
(1) The likelihood of experiencing a bone fracture, which can be influenced by factors such as bone mineral density and the presence of conditions like osteoporosis.[12] (2) Fracture risk is the likelihood of bone fractures occurring, which increases if the kidney function keeps declining.[13] (3) This is the probability of a bone breaking, and is associated with low bone mineral density.[14]
From: Sustainability Journal (MDPI)
(1) Large tension resulting from very short mooring lines may increase the fracture risk.[15]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) The calculated probability or likelihood that an individual will experience a broken bone, often assessed in the context of different metabolic conditions.[16] (2) The probability of an individual breaking a bone, which was assessed in children participating in a multi-year exercise regimen to see if mass gains were detrimental.[17] (3) The probability of sustaining a broken bone, which was analyzed in a systematic review and meta-analysis to see if there was a discernible connection to the specific age at which women entered the post-menopausal phase of life.[18]
From: International Journal of Pharmacology
(1) Fracture risk is a key concern in osteoporosis, and while bisphosphonates aim to reduce it, their effectiveness in this regard is subject to ongoing debate and research.[19] (2) The likelihood of experiencing a bone fracture, which is influenced by bone mass, microarchitecture, and material properties.[20] (3) The role of IGF-1 in influencing fracture risk among men is examined in a referenced publication.[21]