Significance of Fatty change
Fatty change is a histological feature that indicates lipid accumulation within liver cells, commonly observed in conditions such as diabetes and hepatotoxicity. It reflects metabolic disturbances and can be a response to various factors, including S. surattense treatment and CCl4 intoxication. This accumulation of fat in liver tissue suggests potential liver damage and highlights the importance of monitoring liver health in diabetic rats and other affected organisms.
Synonyms: Steatosis, Fatty degeneration, Hepatic steatosis, Lipid accumulation, Fatty infiltration, Hepatic steatosis.
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The concept of Fatty change in scientific sources
Fatty change denotes fat accumulation in the liver, signaling potential liver damage, often linked to hepatotoxicity. It also appears in liver tissues of diabetic rats and can improve with S. surattense treatment.
From: World Journal of Pharmaceutical Research
(1) A pathological condition where fat accumulates in liver cells, a common response to CCl4 intoxication.[1] (2) A condition where fat accumulates in liver cells, reflecting metabolic disturbances often observed in diabetes.[2] (3) Accumulation of fat within the liver, which can be indicative of liver damage and is often observed in cases of hepatotoxicity.[3]
From: Journal of Ayurveda and Integrative Medicine
(1) A histological feature observed in liver tissue of diabetic rats, indicating lipid accumulation, which was improved following S. surattense treatment.[4] (2) Metabolic changes in liver cells characterized by the accumulation of fats, often indicative of liver injury or dysfunction.[5]
From: AYU (Journal of Research in Ayurveda)
(1) A pathological condition noted in the kidneys of treated rats, reflecting lipid accumulation that indicates toxicity.[6]