Significance of Experimental animal
Experimental animals are non-human animals utilized in scientific research across various disciplines like Ayurveda, Science, Health, and Environmental Sciences. Commonly, mice, rats, and rabbits are used to study biological processes, diseases, and the effects of treatments under controlled conditions. Studies adhere to ethical guidelines and standard protocols for animal care. These animals aid in evaluating the safety and efficacy of medicinal substances, plant extracts, and various compounds, contributing to advancements in understanding and treating diseases.
Synonyms: Laboratory animal, Test animal, Experimental subject, Animal model
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Experimental animal'
In Hinduism, "Experimental animal" denotes animals utilized in scientific research. Studies involve mice, rats, and rabbits to assess drug effects, toxicity, and medicinal plant properties, under controlled conditions.
From: Journal of Ayurvedic and Herbal Medicine
(1) The experimental animal, specifically the swiss albino mouse, is used in the study to evaluate the analgesic properties of the methanolic extract of Phoenix sylvestris leaves.[1] (2) Experimental animals are the subjects of the study, and they are used to investigate the effects of the plant extracts on their physiology.[2] (3) Experimental animals, specifically Swiss albino mice, were used in the study to assess the antimalarial activity of Capparis tomentosa Lam. extracts against Plasmodium berghei.[3] (4) Experimental animals are used to evaluate and verify the antihyperglycemic potency of Bangladeshi medicinal plants in the current review.[4] (5) These are animals used in experiments to assess the impacts of various substances, as outlined within the context of the provided documents.[5]
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Acute toxicity and laxative studies of Triphala extract are conducted in experimental animals, highlighting the use of animal models to assess the safety and efficacy of Triphala.[6] (2) These are the specific mice used in the experiment, housed under standard conditions with controlled temperature, humidity, and light cycles.[7] (3) These are the animals, the rats and mice, used in the study to assess the effects of the different drugs and treatments.[8] (4) This phrase indicates the animals used in the study, specifically Wistar Albino rats, which were subjected to various treatments and evaluations.[9] (5) These are the wistar strain albino rats selected from the Animal house of SDM Center for Research in Ayurveda and Allied sciences, Udupi that are used in the study.[10]
From: International Research Journal of Ayurveda and Yoga
(1) In experimental animals in the presence of colonization or infection, it would be more appropriate to determine the wound healing potential.[11]
The concept of Experimental animal in scientific sources
Experimental animal refers to animals like mice, rats, rabbits or primates used in controlled scientific studies. These studies test hypotheses, evaluate biological effects, and assess substance safety under controlled conditions.
From: International Journal of Pharmacology
(1) Experimental animals were handled following ethical guidelines, and they had free access to standard feed pellets and water ad libitum.[12] (2) These are animals used in research to study the effects of treatments or substances, in this case, male rats used to assess the biological activity of the complex.[13] (3) Experimental animals included forty adult male albino rats weighing between 180 and 250 g, obtained from King Fahd Animal House, Jeddah, Saudi Arabia, for the study.[14] (4) GST concentration of normal animals was estimated as 5.32 0.56 μmole of CDNB conjugate formed/min/mg protein and it has been reduced to 2.81±0.50 µmole of CDNB conjugal.c formed/min/mg protein by The induction of p-DAB, which is restored back to the level of 4.17=0.45 µmole of CDNB conjugate formed/min/mg protein after the oral administration in experimental animals.[15] (5) Female C57BL/6 mice and male ICR mice were purchased from specific laboratory animal companies and acclimatized before use in experiments.[16]
From: Onderstepoort Journal of Veterinary Research
(1) A total of 10–16 of these were randomly selected and examined monthly at each of the three study sites.[17] (2) Animals used in research, whose welfare is overseen by an ethical committee.[18] (3) These are the animals used in the study, and they were given reduced doses of diminazene to assess the effect on vaccine reactions, and they were also monitored for reactions.[19] (4) These are animals that are used in experiments, and the study uses merino sheep to test the immune responses.[20] (5) These are animals used in research to further investigate the hypothesis regarding Trichinella spp. larvae and their predilection for certain muscle groups and how the distribution patterns are established.[21]
From: Asian Journal of Pharmaceutics
(1) Forty-eight adult male Sprague Dawley rats were used in the study and maintained under controlled conditions.[22] (2) Some flavonoids silymarine, rutin, and catechin were evaluated and compared with amifostine in a mice model.[23] (3) The gel containing extract Аloe arborescens and Quercus cortex was added on the gums of these animals.[24] (4) MCP and sugar beet pectin increased TGI and ILS in these, demonstrating radio-protective properties.[25] (5) These were fed in accordance with detailed feeding rules, with some receiving the apistimul preparation.[26]
From: The Malaysian Journal of Medical Sciences
(1) These are animals used in scientific studies, and the neurotoxicity of pyrethroids on their brains is well-established.[27] (2) Experimental animal refers to the models used in the studies, which aimed to investigate the effects of saffron extract on lipid profile, focusing on in vivo models.[28] (3) In vivo absorption, metabolism, and urinary excretion of alpha, beta-unsaturated aldehydes in these has relevance to the development of cardiovascular diseases.[29] (4) This term refers to the six-week-old male or female albino mice used in the study to assess the effects of the P. foetidus leaf extract.[30] (5) Experimental animals, specifically Sprague Dawley rats, were used to study the effects of minocycline, a neuroprotective agent, on brachial plexus injury, with the C7 nerve roots being avulsed.[31]
From: Journal of Medicinal Plants for Economic Development
(1) A total of 24 albino rats of both sexes were used for the study, allowing for a controlled investigation of the effects of the treatments.[32] (2) These are animals used in research to test the effects of substances, and the study used Wistar rats as a model.[33] (3) These were mature non-pregnant female albino mice, which were obtained from the animal house and were handled according to standards.[34] (4) This term refers to the Wistar rats used in the study, and they are used to evaluate the potential toxicity of the extracts.[35] (5) These are the mice used in the study to evaluate the acute toxicity, analgesic, and anti-snake venom properties of the extracts and isolated compounds, which are crucial.[36]
From: Journal of Public Health in Africa
(1) Experimental animals were the white rats that were used in the study, and the procedure for treating these animals received approval from the Research Ethics Commission.[37] (2) These are used to test the effect of streptozotocin, and the study looked at the effect of mangosteen peel on proinflammatory cytokines by inhibiting TNF-α.[38] (3) Experimental animals were used to induce a gastro food allergy model, and the SAE-sensitized group experienced an increase in systemic allergic symptoms during the challenge periods.[39] (4) These are the Rattus norvegicus mice used in the study, which were adapted to room temperature before being given the Rhodamine B treatment.[40] (5) The female white rats (Rattus norvegicus) Wistar strain used in the research, obtained from the Animal Laboratory, Faculty of Pharmacy, Universitas Airlangga, as the text describes.[41]
From: Journal of Metabolic Health
(1) This term refers to the rats used in the study, which were subjected to various treatments and observations to evaluate the effects of tannins on diabetes.[42]
From: South African Journal of Physiotherapy
(1) This term is used in conjunction with blood pressure measurement, indicating a focus on research involving the measurement of blood pressure in both humans and animals.[43]
From: International Journal of Pharmacology
(1) White sexually mature male Wistar rats used in the study to examine ricinine distribution after oral intoxication with castor seeds suspension.[44] (2) These were used to evaluate the antinociceptive and anti-inflammatory properties of various plant extracts.[45] (3) Animals used in scientific research to study biological processes, disease mechanisms, or the effects of treatments.[46] (4) These were the rats that received the compound AA-2 or the ethyl acetate extract as part of the toxicity study.[47] (5) Experimental animals, specifically Swiss-Webster strain mice, were used to study the effects of nicotine and green tea extract on offspring.[48]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) "Experimental animals" exposed to pesticide have shown reductions in splenic plaque forming cells, suggesting impaired humoral immunity.[49] (2) Denotes non-human organisms used in research to study the effects of air pollutants on biological processes and health.[50] (3) Experimental animals are animals used in scientific research to study biological processes or test the effects of treatments, and RFR exposure has not been considerably linked to an increased incidence of tumors at any site both in rats or mice exposed for 24 months at di ff erent RFR intensities in experimental animals.[51] (4) Subjects in which high concentration levels of a certain substance have been described in the liver, gallbladder, and epididymis after exposure.[52] (5) Experimental animals, specifically sixteen male Otsuka Long-Evans Tokushima Fatty (OLETF) rats, were randomly assigned to diabetic control and diabetic exercise-trained groups.[53]
From: International Journal of Pharmacology
(1) These are the male Sprague Dawley rats and male Balb/C mice used in the experiments, adapted to laboratory conditions.[54] (2) These are the rats that were used in the experiment to study the effects of rutaecarpine on diabetic cataracts.[55] (3) This refers to the albino wistar rats and albino mice that were used in the study to test the effects of the root extract on various conditions, such as pain and inflammation.[56]
From: South African Journal of Psychiatry
(1) Something that the chick may also serve as a useful to help understand such aspects of the autistic disorders.[57]