Significance of Epigenetic modification

Epigenetic modification refers to changes in gene expression that occur without altering the DNA sequence, primarily influenced by environmental factors such as diet and nutritional status. These modifications can involve processes like DNA methylation and histone modification. They play a crucial role in health outcomes, particularly during critical periods like pregnancy, and can affect responses to treatments and the development of disorders, including cancer. Additionally, epigenetic changes can be reversible and inherited by daughter cells, offering potential therapeutic avenues.

Synonyms: Epigenetic alteration, Epigenetic change, Epigenetic regulation, Genetic modification, Dna methylation, Histone modification, Chromatin remodeling, Gene silencing

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

Hindu concept of 'Epigenetic modification'

Hinduism Books

In Hinduism, Epigenetic modification symbolizes the interplay between lifestyle choices and genetic expression, emphasizing that one's external habits—such as diet, exercise, and stress management—can fundamentally influence their inner nature and spiritual evolution.

Significance in Ayurveda (science of life):
Ayurveda Books

(1) These are changes to the chromosome that alter gene expression, and are influenced by lifestyle factors like diet, exercise, and stress management.[1]

Ayurveda is a branch of Indian science dealing with medicine, herbalism, taxology, anatomy, surgery, alchemy and related topics. Traditional practice of Ayurveda in ancient India dates back to at least the first millenium BC. Literature is commonly written in Sanskrit using various poetic metres.

The concept of Epigenetic modification in scientific sources

Science Books

Epigenetic modification involves changes to DNA that influence gene expression without altering the actual DNA sequence, playing a significant role in processes such as cancer development, according to regional sources.

Significance in Scientific journals, articles, etc.:

(1) This refers to changes in gene expression that do not involve alterations to the DNA sequence itself, such as DNA-methylation.[2] (2) These modifications can be reversed by removing the epimarks or tags which causes behavioral changes in individuals, based on environmental experiences.[3]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.

Plural form: Epigenetic modifications.