Significance of Effective dose
Effective dose is a critical concept in pharmacology, representing the specific quantity of a drug necessary to achieve the desired therapeutic effect. In the study, this is quantified at various levels, such as 200 mg/kg/dose for general therapeutic benefits and 50 mg/kg for synthesized compounds. Additionally, effective dose is concerned with balancing efficacy and safety by determining the amount that elicits beneficial effects without adverse reactions. This measurement is essential for optimizing treatment protocols and ensuring patient safety.
Synonyms: Therapeutic dose, Optimal dose, Effective amount, Dosage, Medicinal dose, Recommended dose, Suitable dose, Proper dose, Appropriate dose, Adequate dose
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Effective dose'
In Hinduism, "Effective dose" signifies the optimal quantity of Changeri Masi required to effectively purify contaminated water by removing copper, highlighting a significant discovery in environmental treatment methods.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) This is the specific amount of Changeri Masi found to be most successful in removing copper from the contaminated water, which is a key finding of the study.[1]
From: Journal of Ayurvedic and Herbal Medicine
(1) This is the amount of saffron needed to produce a desired effect, and more research is needed to determine the correct dosage for various conditions.[2]
From: International Research Journal of Ayurveda and Yoga
(1) It is the calculated amount of the powdered drug intended to produce a therapeutic effect.[3]
The concept of Effective dose in scientific sources
Effective dose pertains to the specific quantity of a drug required to elicit the desired therapeutic effect in clinical studies, serving as a key indicator for dosing in medical treatments.
From: The Malaysian Journal of Medical Sciences
(1) Effective dose of antiplatelet drugs can be administered to patients with persistent thrombotic complications, which can be determined by titrating the dose and offering a customized prophylactic therapy.[4] (2) Effective dose refers to a specific amount of morphine determined to produce the intended results in the behavior assessment during experimentation.[5] (3) A measure used in dosimetry metrics to assess the radiation dose absorbed by a person, factoring in the sensitivity of different tissues.[6] (4) A dose measurement defined by the International Commission on Radiological Protection, representing the absorbed radiation dose across tissues and organs, weighted for sensitivity.[7]
From: Onderstepoort Journal of Veterinary Research
(1) The amount of a stabilate required to achieve a specific level of infectivity, often expressed as ED50, and used in both in vitro and in vivo studies to assess the efficacy of immunization.[8] (2) This refers to the quantities of the stabilate that result in a given proportion of wells to be positive, and ratios were calculated to compare sporozoite infectivities.[9]
From: International Journal of Pharmacology
(1) The Effective dose 50 (ED 50 ) of G-A for the percentage of TOA was 0.44 mg kg G 1 and maximal Effect (Emax) was 55.84%, while for percentage of EOA, the ED 50 was 0.51 mg kg G 1 with Emax = 55.98%.[10] (2) As group IV treated with 500 mg kg –1 b.wt. of ethanolic extract of P. longiflora Rudolph, showed better antidiabetic response among test groups, hence, this dose can be considered as ideal for antidiabetic effect.[11]
From: South African Family Practice
(1) The dose of a drug that produces the desired effect, and the text recommends using the lowest effective dose possible.[12]
From: Asian Journal of Pharmaceutics
(1) The present study concludes that these erodible mucoadhesive buccal films containing olmesartan can be very promising for effective doses to systemic circulation.[13]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Relates to the radiation exposure level, with a reference level set by the ICRP corresponding to a specific amount per year.[14] (2) Refers to a measure of the risk of health detriment due to exposure to ionizing radiation, taking into account the type of radiation and the organs irradiated.[15] (3) Acceptable effective doses for medical personnel have been established due to the fact that it is impossible to completely avoid exposure while working in a NM department.[16] (4) Effective dose refers to the amount of medication needed to produce the desired therapeutic effect, and the text recommends prescribing antidepressants at the lowest effective dose during breastfeeding to minimize potential risks to the infant.[17] (5) It is a measure of radiation exposure adjusted for the sensitivity of different tissues and organs, which is examined in relation to cancer incidence among diagnostic radiation workers.[18]
From: Sustainability Journal (MDPI)
(1) This represents the total radiation exposure received, measured in mSv per year, and is categorized by age group for surface water samples.[19]