Significance of Drug stability

Drug stability refers to the ability of a pharmaceutical compound to maintain its physical, chemical, and microbiological properties over time, particularly in various biological and environmental conditions. It encompasses crucial factors such as identity, strength, purity, and potency throughout the drug's shelf life. Evaluations are conducted through analytical procedures, ensuring the drug remains effective and safe for use. Maintaining drug stability is essential for the formulation of different dosage forms, including oral suspensions, and impacts therapeutic efficacy and safety.

Synonyms: Pharmaceutical stability

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

The concept of Drug stability in scientific sources

Science Books

Drug stability is the ability of a pharmaceutical formulation to maintain its effectiveness and integrity—physically, chemically, microbiologically, and therapeutically—under specific storage conditions throughout its shelf life.

Significance in Scientific journals, articles, etc.:

From: World Journal of Pharmaceutical Research

(1) The capacity of a drug to maintain its physical and chemical properties over time.[1] (2) The ability of a drug to maintain its efficacy and remain unchanged under specific conditions.[2] (3) The capability of a drug formulation to maintain its identity, strength, quality, and purity throughout its shelf life.[3] (4) Refers to the drug's resistance to degradation due to environmental factors like acid/base hydrolysis when administered orally, which is crucial for maintaining bioavailability.[4] (5) The ability of a drug to maintain its identity, strength, quality, and purity through its shelf life or during storage.[5]

From: Journal of Ayurveda and Holistic Medicine

(1) The capability of a pharmaceutical formulation to remain effective without changes to its physical, chemical, microbiological, or therapeutic properties under defined storage conditions.[6]

From: International Ayurvedic Medical Journal

(1) The capacity of a drug formulation to maintain its physical, chemical, therapeutic, and toxicological integrity over time.[7]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.