Significance of Drug resistance
Synonyms: Antimicrobial resistance, Medication resistance, Pharmacological resistance, Drug tolerance, Therapeutic resistance, Antibiotic resistance
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Drug resistance'
From: Journal of Ayurvedic and Herbal Medicine
(1) This is a challenge in prostate cancer treatment, and the study aims to find natural compounds like CBD and THC that could overcome this issue and provide alternative treatment options.[1] (2) This is the ability of a parasite to withstand the effects of a drug, making the treatment ineffective. The development of resistance to antimalarial drugs is a significant concern, prompting the use of drug combinations to enhance activity and delay resistance.[2] (3) This is a major issue in the pharmaceutical field due to the serious economic loss and time, which occurs when a drug loses its effectiveness.[3] (4) The text discusses how resistance to antimalarial drugs has developed, making it more difficult to control malaria and endangering existing programs that combat the disease, and is a significant challenge.[4] (5) This is the ability of bacteria to withstand the effects of drugs, and the use of local drug delivery can reduce drug resistance, as mentioned in the introduction.[5]
From: International Research Journal of Ayurveda and Yoga
(1) New and improved antiviral drugs are in demand in the current scenario for the prophylaxis as well as treatment of a large number of viral diseases.[6] (2) Although synthetic drugs are having better results for treating depressive disorders, one cannot avoid major side effects such as this.[7] (3) Prolonged use of antihistamines and antibiotics leads to drug resistance.[8]
From: Journal of Ayurveda and Integrated Medical Sciences
(1) The ability of microorganisms to withstand the effects of antimicrobial drugs, a growing concern that has led to increased interest in alternative treatments like those derived from plants.[9] (2) This is the ability of microbes to withstand the effects of drugs, and it is a significant problem that prompted the search for alternative antimicrobial agents, such as plant extracts.[10]
The concept of Drug resistance in scientific sources
From: South African Journal of HIV Medicine
(1) It is the reduced susceptibility of viruses to antiretroviral drugs, potentially compromising treatment effectiveness and requiring alternative regimens.[11] (2) The switch from NNRTI-based therapy to TLD can be made regardless of the patient’s VL, since both 3TC/FTC and TDF can be recycled with DTG, whether or not there is resistance to these drugs.[12] (3) It is the resistance to DTG that is of public health relevance.[13] (4) This refers to the ability of microorganisms, such as viruses, to withstand the effects of drugs intended to kill them, such as those used in the treatment of HIV.[14] (5) This is a concern regarding rapid scale-up programs in resource-poor settings, although there is no empirical evidence that it is more problematic in developing countries than developed countries.[15]
From: International Journal of Pharmacology
(1) Systemic toxicity can contribute to drug resistance, making traditional chemotherapy ineffective in overcoming multidrug resistance, which is responsible for early or late recurrence.[16] (2) Drug resistance in A. salmonicida was first reported in the USA with the finding of strains resistant to sulphonamides and has tended to follow drug usage.[17] (3) Induction of SULTs increases xenobiotic detoxification, but at the same time, SULT induction can also cause this.[18] (4) The ability of parasites to withstand the effects of drugs, paving the way for herbal alternatives.[19] (5) Wenxia Changfu formula (WCF) induced cell apoptosis, arrested the cell cycle in the G1 phase and reversed this to DDP by downregulating the expression of integrin β1, FAK, PI3K and AKT.[20]
From: Asian Journal of Pharmaceutics
(1) This is the ability of microorganisms to withstand the effects of drugs, leading to treatment failure.[21] (2) Resistance to trastuzumab emtansine, according to Breast Cancer Research.[22] (3) The ability of parasites to withstand the effects of antimalarial drugs, complicating malaria treatment.[23] (4) Investigate the potential of nanocarriers in facilitating combination therapies for synergistic effects and overcoming this.[24] (5) This development of microbial strains has made it necessary to investigate the influence of pyrazole compounds on biological systems. The continuous search for novel biologically active pyrazole derivatives is coupled with this.[25]
From: Onderstepoort Journal of Veterinary Research
(1) Drug resistance plasmid study in Salmonella enterica isolates of domestic animals and lizards has been conducted in some southwestern states of Nigeria.[26] (2) A factor that contributes to the emergence and re-emergence of diseases.[27] (3) The ability of worms to withstand the effects of anthelmintic drugs, which is a major concern for farmers, driving the adoption of methods like the FAMACHA© system.[28] (4) The validation of markers associated with this condition is illustrated using population genetics as a methodology, drawing upon examples from other parasitic protozoa, as discussed in the text.[29] (5) This is a significant concern, alongside drug residues in poultry meat, which presents challenges to relying on drugs for long-term control of a specific chicken disease.[30]
From: South African Family Practice
(1) Drug resistance occurs when a virus, such as HIV, mutates and becomes less susceptible to the effects of antiretroviral medications, leading to treatment failure and requiring a change in medication.[31] (2) Drug resistance is an emerging concern in tuberculosis treatment, particularly multi-drug resistant and extensively drug-resistant strains, which require different treatment approaches.[32] (3) Poor adherence to ART is highly predictive of viral load and drug resistance, leading to resistance to treatment and the need for more expensive medication.[33] (4) This is the ability of a virus to withstand the effects of a drug, and poor adherence to antiretroviral therapy (ART) is highly predictive of it.[34] (5) This refers to the situation when drugs become ineffective against diseases, which is a threat to the treatment of HIV and HBV.[35]
From: The Malaysian Journal of Medical Sciences
(1) Emerging resistance to available drugs highlights the need for new drugs and vaccines to control leishmaniasis.[36] (2) This is the ability of microorganisms to withstand the effects of drugs, and it is a major concern in the context of studying specific types of bacteria, and it is a focus of research.[37] (3) This is a phenomenon that can affect the outcomes of the treatment of the infections, affecting the analysis.[38] (4) This is the ability of bacteria to withstand the effects of drugs, which is a major challenge in the treatment of infectious diseases.[39] (5) This is a concern, and the study examined the patterns of resistance to various antibiotics, as highlighted within the provided text.[40]
From: Journal of Public Health in Africa
(1) Care Seeking activities in health facilities need to be evaluated because if the intended care provider is not appropriate then the case non-pneumonia can lead to this.[41] (2) This is a significant concern in HIV treatment, and the study investigates its development and impact on treatment outcomes.[42] (3) The text highlights the potential impact of increased self-medication on drug resistance, underscoring the need to explore these effects through innovative data science tools.[43] (4) This refers to a phenomenon, and the public implications of antiretroviral therapy and this are being discussed.[44] (5) Herbs may interact with antiretroviral drugs, and these interactions can lead to this, and treatment failure.[45]
From: African Journal of Primary Health Care and Family Medicine
(1) This is when the HIV virus develops the ability to resist the effects of antiretroviral medications, which can result from inconsistent treatment and lead to treatment failure.[46] (2) This refers to the situation where a medication, such as those used in antiretroviral therapy, becomes less effective in treating a disease because the pathogen, such as HIV, has developed a resistance to it.[47] (3) Drug resistance refers to the ability of bacteria, such as those causing tuberculosis, to withstand the effects of medications designed to kill them, complicating treatment.[48] (4) This can be prevented through timely and effective TB treatment, and monitoring DR-TB treatment outcomes is critical when evaluating TB control strategies, and this is a significant factor.[49] (5) This is the ability of microorganisms to withstand the effects of drugs, and it poses a major threat to treating cholera, necessitating regular surveillance during outbreaks to monitor and manage the issue.[50]
From: Journal of Medicinal Plants for Economic Development
(1) The text often discusses drug resistance, which is the ability of microorganisms to withstand the effects of drugs, and this is a major concern driving the search for new treatments.[51] (2) This is the ability of microorganisms to withstand the effects of drugs, which has increased and necessitated the bioprospecting of plants.[52] (3) The ability of microorganisms to withstand the effects of drugs, which is a challenge in the treatment of oral candidiasis and other fungal infections.[53]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) The ability of microorganisms to withstand the effects of antimicrobial drugs, posing a significant challenge to infection control and treatment.[54] (2) Drug resistance is the ability of pathogens to withstand the effects of medications designed to kill or inhibit them, leading researchers to explore traditional folk remedies as viable treatment options due to the increased incidence of drug-resistant pathogens.[55] (3) β-Lactamases confer drug resistance to bacteria by degrading β-lactam antibiotics, highlighting their role in antibiotic resistance mechanisms.[56] (4) One reference touches on the multiple facets of drug resistance, emphasizing its role as a rising challenge in the 21st century and the necessity for comprehensive research and development efforts.[57] (5) Drug resistance is a characteristic of malaria parasites examined through molecular markers in endemic sites, which affects the effectiveness of treatments.[58]
From: Sustainability Journal (MDPI)
(1) The multi-target mechanism of action, resulting from the synergistic effect of 2 e and EO 1, is beneficial in reducing the drug resistance of bacteria.[59] (2) Drug resistance is examined in the marine environment, with this examination contributing to a broader understanding of the phenomenon.[60] (3) This is the ability of microorganisms, such as bacteria or viruses, to withstand the effects of medications designed to kill or inhibit them.[61]
From: International Journal of Pharmacology
(1) Drug resistance is a phenomenon where pathogens, like malaria parasites, become less susceptible to the effects of drugs used to treat them.[62] (2) This phenomenon in cancer is discussed broadly, covering various aspects of how cancer cells evade treatment.[63] (3) This is a common cause of therapeutic failure in extracranial solid tumors in children and is a frequent feature of brain tumors.[64] (4) A situation closely related to the indiscriminate use of antibiotics worldwide, encouraging scientists to seek novel antimicrobial compounds from various sources.[65] (5) The phenomenon where cancer cells become less responsive to treatment over time, a major challenge in systemic therapy for breast cancer that necessitates alternative approaches.[66]
From: South African Journal of Psychiatry
(1) This describes the ability of a virus, such as HIV, to evolve and become less susceptible to the effects of medications, making it more challenging to treat the infection and manage the disease effectively.[67]