Significance of Drug modification
Drug modification, according to Health Sciences, has two distinct meanings. First, it describes a process where microorganisms develop resistance to antimicrobial drugs through enzymatic deactivation. Second, in the context of transdermal drug delivery, drug modification represents one category of strategies used to improve drug penetration across skin barriers. This approach aims to overcome challenges in delivering drugs effectively through the skin.
Synonyms: Alteration, Change, Adjustment, Refinement, Enhancement, Transformation, Drug metabolism, Drug derivatization
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The concept of Drug modification in scientific sources
Drug modification involves enzymatic deactivation by microorganisms, causing antimicrobial resistance. It also describes transdermal enhancement strategies that overcome drug delivery barriers.
From: Asian Journal of Pharmaceutics
(1) This is one of five groups into which transdermal enhancement strategies have been divided, to overcome barriers to drug delivery.[1] (2) This is a mechanism by which microorganisms exhibit resistance to antimicrobial drugs, involving enzymatic deactivation.[2]