Significance of Drug Interaction
Drug Interaction refers to the influence one drug can have on another, potentially altering its efficacy and safety. This phenomenon can occur due to the concurrent use of multiple medications, foods, or other substances, leading to various adverse effects. Such interactions may complicate treatment regimens, particularly in vulnerable populations or when managing specific conditions like TB and HIV co-infection. Therefore, understanding drug interactions is crucial for effective patient care and medication management.
Synonyms: Drug-drug interaction, Pharmacological interaction
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Drug Interaction in scientific sources
Drug Interaction describes how one medication can influence the activity of another, which may result in adverse effects, particularly concerning combinations of Ayurvedic, allopathic medicines, and spices with modern drugs, highlighting potential health risks.
From: World Journal of Pharmaceutical Research
(1) The effects that occur when the pharmacological activity of one drug is modified by another drug, which can lead to increased toxicity or reduced efficacy.[1] (2) The effects that may occur when two or more drugs interact, leading to altered expected effects or increased risk of adverse effects.[2] (3) Phenytoin has known drug interactions with medications such as amiodarone and certain hormonal pills.[3] (4) Drug interactions refer to the effects that occur when phenytoin is taken alongside other medications, potentially leading to toxicity.[4] (5) The respective effects seen when two or more drugs interact in the body, potentially leading to harmful side effects or reduced effectiveness.[5]
From: Journal of Ayurveda and Integrative Medicine
(1) The effects that occur when different substances, including herbal medicines and conventional drugs, are taken together, which can influence treatment outcomes.[6] (2) The effects that may occur when a drug interacts with another drug or substance, which is relevant for a phytopharmaceutical like P.kurroa-Kutki.[7] (3) The study of how different medications interact, crucial for patients using multiple healthcare systems.[8] (4) The effect that one drug or substance has on the pharmacokinetics and pharmacodynamics of another, as investigated in the context of green tea and hydrochlorothiazide.[9] (5) The potential effects that occur when Triphala is used alongside other medications, such as tamsulosin and oxycodone.[10]
From: Journal of Ayurveda and Holistic Medicine
(1) The effects that occur when spices are consumed alongside modern medications, potentially leading to harmful outcomes.[11] (2) The effect that occurs when one drug alters the activity of another drug, potentially leading to adverse effects, particularly in the context of Ayurvedic and allopathic medicines.[12] (3) Interactions between two or more drugs that can alter the effectiveness or cause adverse effects; can occur between drugs, foods, or other substances.[13]
From: International Ayurvedic Medical Journal
(1) The effects that occur when a drug or herb combines with another substance, potentially altering its efficacy or safety.[14] (2) The effect that one drug may have on the efficacy or side effects of another, which is particularly relevant in the context of combining Ayurvedic treatments with conventional medications.[15] (3) A situation where the effect of a drug is altered due to interactions with other drugs, foods, or herbs.[16]
From: Journal of Indian Society of Periodontology
(1) The effect that one drug may have on another, possibly affecting the efficacy or safety of treatment, particularly relevant in systemic therapies.[17] (2) A situation where one substance affects the activity of another drug, important to consider for a patient taking multiple medications.[18]
From: The Malaysian Journal of Medical Sciences
(1) Risks of negative reactions arising from the combination of herbal supplements and other medications that patients may be taking.[19] (2) Situations where the effects of one drug are altered by the presence of another drug, food, or other substance, potentially impacting patient safety and treatment efficacy.[20]
From: Ancient Science of Life
(1) The effects that occur when two or more drugs influence each other's activity, potentially leading to increased adverse effects or reduced efficacy.[21]
From: AYU (Journal of Research in Ayurveda)
(1) The effects that occur when two or more drugs, including herbal medicines, are administered together, which can lead to adverse reactions.[22]