Significance of Drug Disposition
Drug disposition encompasses the processes of absorption, distribution, metabolism, and elimination of drugs in the body. It is influenced by various factors, including solubility, which plays a significant role in how drugs are distributed post-administration. Understanding drug disposition is vital for assessing therapeutic efficacy, as it directly impacts how effectively a drug can achieve its desired effects in the body.
Synonyms: Drug distribution, Drug metabolism, Drug pharmacokinetics, Drug absorption, Drug elimination, Drug excretion, Drug transport., Drug clearance
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The concept of Drug Disposition in scientific sources
Drug Disposition is influenced by solubility, impacting the distribution of drugs throughout the body following administration. This relationship highlights the importance of solubility in the effective therapeutic delivery of medications.
From: International Journal of Pharmacology
(1) The overall process of drug absorption, distribution, metabolism, and excretion in the body.[1]
From: International Journal of Pharmacology
(1) The movement of a drug within the body, which can be modified by genetic characteristics affecting metabolism and leading to side effects.[2] (2) Drug disposition refers to how a drug moves through the body, including absorption, distribution, metabolism, and excretion.[3] (3) This term refers to how a drug is distributed, metabolized, and eliminated from the body, and it can be affected by pathophysiological conditions.[4]