Significance of DNA vaccine
DNA vaccines are a modern approach to immunization. They use genetically engineered DNA, often in the form of plasmids, to stimulate an immune response against specific diseases. These vaccines work by introducing DNA encoding a specific antigen, prompting the body to produce the antigen and mount an immune defense. This method is being explored for various diseases, including COVID-19, tuberculosis, rotavirus, and even cancer, offering a potentially safer and more effective way to protect against pathogens.
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Hindu concept of 'DNA vaccine'
In Hinduism, a DNA vaccine could be interpreted as a scientific intervention. It is a method that introduces genetic material to stimulate an immune response, as observed in the study on mice, potentially aligning with concepts of health and well-being.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) The text describes a type of vaccine and its effects in the context of a study involving mice.[1]
The concept of DNA vaccine in scientific sources
DNA vaccines employ genetically engineered DNA plasmids, acting as vectors. They stimulate immune responses by encoding antigens, inducing immunity against pathogens like heartwater, Ebola, and rotavirus. These vaccines are being explored for various diseases.
From: The Malaysian Journal of Medical Sciences
(1) These consist of a closed circular bacterial plasmid that encodes the antigen of interest under the control of a strong eukaryotic promoter, after transfection.[2] (2) The vaccine prototype is currently being tested as a DNA vaccine delivery vector for immunisation against COVID-19 and tuberculosis, according to the provided information.[3] (3) A vaccine that uses DNA to stimulate an immune response, and in this context, the recombinant plasmid containing the TSA gene is considered a potential one.[4] (4) This type of vaccine uses DNA encoding a specific antigen to stimulate an immune response and is used in malaria research.[5] (5) Vaccines that use genetically engineered DNA to induce an immune response against viruses such as Ebola.[6]
From: Onderstepoort Journal of Veterinary Research
(1) A deoxyribonucleic acid vaccine is being developed against heartwater, with the goal of creating a safe, affordable, and effective solution that does not require transport on dry ice.[7] (2) DNA vaccine vectors are being used in recombinant vaccine development, and they have shown promise in stimulating immunity against heartwater, though they may need boosting.[8] (3) This is a type of vaccine that uses DNA to stimulate an immune response against a pathogen, such as Ehrlichia ruminantium, potentially providing protection against heartwater.[9] (4) This is a type of vaccine that uses DNA to stimulate an immune response, and this study investigated the immunogenicity of a plasmid DNA vaccine encoding the G1 epitope of bovine ephemeral fever virus G glycoprotein in mice.[10] (5) A type of vaccine that uses DNA to stimulate an immune response, which is a newer approach for protecting animals and children against the rotavirus.[11]
From: International Journal of Pharmacology
(1) Use of various adjuvants such as CpG ODN has been found to enhance antibody production with these.[12] (2) The use of this is an attractive approach for generating antigen-specific immunity to various pathogens because of its stability and simplicity of delivery.[13] (3) Vaccines that express proteins of the virus along with other vectors (viral) that express antigens of the virus can be explored.[14] (4) DNA vaccines can incorporate immunomodulators, according to the text.[15] (5) A newer type of vaccine that has been developed for CIAV but requires further application.[16]
From: Asian Journal of Pharmaceutics
(1) The result shows that DNA can be effectively entrapped within a range of nonionic vesicles formulation using the dehydration-rehydration method and these vesicles containing DNA, may be a useful system for subcutaneous delivery of DNA vaccine.[17] (2) A type of vaccine being developed for Alzheimer's disease.[18]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) The VRC is a 3-dose DNA vaccine which encodes PrM and E glycoproteins under a cytomegalovirus-T-cell leukemia virus type I R region promoter, and it has gone under two Phase I clinical trials.[19] (2) DNA vaccines are mentioned as an engineering tool against infectious diseases, indicating their potential in combating viral infections and other ailments.[20] (3) DNA vaccines involve injecting genetic material to produce an immune response, and are included in the vaccine development efforts against Enterovirus 71.[21]