Significance of DNA methylation
DNA methylation, a key epigenetic mechanism, involves adding a methyl group to DNA. This process influences gene expression without altering the DNA sequence and is linked to various health conditions. It can affect gene expression, silence tumor suppressor genes, and potentially lead to diseases like cancer and stroke. DNA methylation is dynamic, affected by environmental interactions, and crucial in regulating gene expression and potentially memory formation.
Synonyms: Gene methylation, Methylation, Cytosine methylation, Epigenetic modification, Gene silencing, Epigenetic regulation, Gene expression regulation
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Hindu concept of 'DNA methylation'
In Hinduism, DNA methylation, an epigenetic process, involves adding a methyl group to DNA. This process potentially regulates chromatin, influencing Prakriti's unique phenotypes. It's linked to depression and discussed in relation to the condition's causes and effects.
(1) This is a process that involves the addition of a methyl group to a DNA molecule, which may play a role in chromatin regulation, influencing the distinct phenotypes of Prakriti.[1] (2) This is an epigenetic mechanism that is associated with depression, and is discussed in the context of the causes and effects of the condition, as stated in the text.[2]
The concept of DNA methylation in scientific sources
DNA methylation is a dynamic epigenetic process involving adding methyl groups to DNA, primarily at cytosine residues. This modification influences gene expression, potentially silencing genes and impacting various biological processes, including disease development. It's a crucial mechanism in epigenetic regulation.
(1) This is a process that alters DNA and the text states that IDH1 mutations result in changes in the DNA methylation pattern, which are associated with NPM1 mutations.[3] (2) This is the most common epigenetic modification, which is inherited without alteration in the primary gene sequence, and it can influence the risk of ischaemic stroke.[4] (3) This is a type of epigenetic change that involves the addition of a methyl group to DNA, which can be altered by environmental interactions and may lead to changes in memory formation and brain cell function.[5] (4) An epigenetic mechanism that modifies gene expression, potentially leading to the activation or silencing of genes involved in cancer progression.[6] (5) A process of adding a methyl group to DNA, which can influence gene expression and is one of the classic examples of epigenetic regulation.[7]
(1) This is a process that can affect gene expression, and it is relevant to breast cancer because it can silence tumor suppressor genes, like BRCA 1.[8]
(1) DNA methylation is a dynamic epigenetic process that requires further investigation to fully understand its role in neuronal function and disease.[9]
(1) By combining this, histone modification and other epigenetic markers, provision can be made for a controllable and highly precise means to regulate the genome.[10]