Significance of Detection limit
Detection limit refers to the lowest concentration of an analyte that can be reliably detected, though not necessarily quantified, under specific experimental conditions. It is a critical parameter in analytical methods, influencing the ability to measure substances accurately. Various analytical techniques, including HPLC and spectrophotometry, establish detection limits for different substances, with values varying based on the method and substance in question. Understanding detection limits is essential for assessing the effectiveness and reliability of analytical assays.
Synonyms: Detection threshold, Sensitivity limit, Threshold, Sensitivity, Quantification limit
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Detection limit in scientific sources
Detection limit is the lowest concentration of a substance, such as cobalt (II) at 0.035 µg/ml, that can be reliably identified in a sample, indicating the sensitivity of analytical methods.
From: The Malaysian Journal of Medical Sciences
(1) This is the lowest amount of the hormone that can be detected, which was 0.75 mIU/ml in this study, and it was well within the physiological range.[1] (2) These are the lower bounds of a sensor's ability to measure a substance, and are influenced by blank and signal fluctuations.[2] (3) Detection limits refer to the minimum DNA quantity detectable by the mPCR assay, which is crucial for determining assay effectiveness.[3]