Significance of Degenerative change
Degenerative change, according to the provided texts, describes a broad range of adverse physical and physiological alterations. These changes encompass structural deterioration in tissues, organs, and joints, often linked to aging, disease, or injury. This can lead to a loss of function, pain, and reduced mobility. The changes are characterized by a progressive decline in the body's structure or function, with the severity often increasing over time.
Synonyms: Deterioration, Degeneration, Decline, Deterioration process, Wasting, Erosion, Degradation, Wear-and-tear, Breakdown, Decay
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Degenerative change'
In Hinduism, degenerative change signifies the physical decline associated with aging. This involves a loss of strength, complexion, and weakened senses. It is linked to Akalaja Jara and Ayurveda, representing alterations in the body's physical and mental state due to aging.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Degenerative changes of vertebral body were observed in all subjects, according to the study of anatomical changes in the lumbar spine.[1] (2) are seen in the health of many people today due to factors like irregular physical activity, unhealthy eating, irregular sleep, continuous computer work, and mental stress.[2] (3) Faulty dietetic habits and irregular life style is responsible for early degenerative changes in bodily tissue and play a vital role in the manifestation of such degenerative disorder.[3] (4) Disc bulge is due to it which is indicative of Vata Prakopa hence Basti may be considered as best treatment.[4] (5) These are the age-associated changes in joint structures that contribute to the development of osteoarthritis.[5]
From: International Research Journal of Ayurveda and Yoga
(1) The text says that perimenopause is a group of symptoms produced by degenerative changes in the body.[6] (2) These are more likely to occur in women as compared to men in the spine.[7] (3) These changes occur in the joint surfaces of the lumbar spine in lumbar spondylosis, leading to degeneration and other complications.[8] (4) These changes in the lower back because of lumber spondylosis can lead to compression of the spinal nerve resulting in lower back pain.[9] (5) These are progressive deteriorations in the structure or function of tissues or organs, and can occur in high myopia.[10]
From: Journal of Ayurvedic and Herbal Medicine
(1) Mild degenerative changes in mid and lower thoracic disc spaces and cervical disc spaces.[11] (2) Degenerative changes refer to the structural changes observed in the patient's spine, as revealed by an MRI, and are a key aspect of the IVDP diagnosis.[12]
The concept of Degenerative change in scientific sources
Degenerative change encompasses various deteriorations, primarily due to aging, disease, or stressors. These changes involve the breakdown of tissues and structures, often affecting joints, organs, and overall bodily functions, leading to various health complications and pain.
From: South African Journal of Physiotherapy
(1) Degenerative changes can affect the margins of cartilage tears within the pubic symphysis, and these changes, unlike haemorrhage, do not typically heal.[13] (2) Alterations occurring in the composition of muscles, tendons, and fibrous tissues, brought about by the repeated small impacts sustained during physical activities over time.[14] (3) These changes may occur in the intervertebral joints, spinal stenosis causing pressure on the nerve root. Rarely, because of an extraforaminal lateral disc herniation.[15]
From: South African Family Practice
(1) Many patients with severe degenerative changes of the lumbar spine do feel much better with support, e.g. a corset, and particularly in the subacute phase.[16] (2) These are a feature of the disease being discussed, as the condition progresses, leading to structural deterioration within the joint, which is reflected in the diagnostic findings and clinical presentation.[17]
From: International Journal of Pharmacology
(1) These are structural and of variable severity, including a hemorrhagic area, observed in certain experimental groups, indicating tissue deterioration.[18] (2) At 20 mg/kg doses, the liver section showed few hepatocytes undergoing these changes in the liver parenchyma.[19] (3) In these, the structure of the nuclei could be seen slightly in the IR group in the experiment.[20]
From: Asian Journal of Pharmaceutics
(1) It also reduced the focal necrosis and degenerative changes in the liver during the treatment according to the text.[21] (2) These changes were observed in the rat submandibular tissues, particularly in the pure arecoline treated group, and lead to an overall decreased salivary output.[22]
From: Onderstepoort Journal of Veterinary Research
(1) These are the changes that indicate a decline in the function or structure of the cells, which were observed in the magnum after carbendazim exposure.[23] (2) These are changes in tissues or organs that result in a loss of function or structure, and these changes were observed in the skeletal muscles of the infected goats.[24]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Structural deterioration within the temporomandibular joint, which can be differentiated from vibration results caused by irregular disc motion by analyzing the Integral greater than 300 Hz component.[25] (2) A longer follow-up period in future research could potentially reveal the long-term aftermath of the initial injury, such as an increased re-operation rate or the development of degenerative changes within the knee joint itself.[26] (3) These changes, concomitant diseases, and a history of falls among older adults over 65 years of age appreciably contribute to overall reduction of individual activity and self-reliance.[27]
From: International Journal of Pharmacology
(1) Alterations in tissue structure indicating damage or deterioration, observed in hyperlipidemic rats and those subjected to renal Ischemia/Reperfusion injury.[28] (2) Pathological alterations in cells or tissues, indicative of damage and dysfunction, observed in diabetic testes.[29] (3) Damage or deterioration of cells, observed in the hepatocytes of rabbits fed a high cholesterol diet.[30]