Significance of Critical temperature
Critical temperature is defined as the maximum temperature that should not be surpassed during primary drying to prevent the 'meltback' or 'collapse' of a formulation. This concept is essential in ensuring the stability and integrity of materials during the drying process, as exceeding this temperature can lead to undesirable outcomes for the product. Understanding and managing the critical temperature is crucial for maintaining the quality of formulations in various scientific applications.
Synonyms: Phase transition temperature, Transition temperature, Boiling point, Melting point, Critical point
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Critical temperature in scientific sources
Critical temperature is the maximum allowable temperature during primary drying that prevents the 'meltback' or 'collapse' of a formulation, ensuring stability and integrity throughout the drying process.
From: World Journal of Pharmaceutical Research
(1) The temperature that must not be exceeded during primary drying to avoid 'meltback' or 'collapse' of the formulation.[1]