Significance of Cotton pellet granuloma
Cotton pellet granuloma is an experimental method used to evaluate chronic inflammation and the efficacy of anti-inflammatory agents. This involves implanting sterile cotton pellets subcutaneously in laboratory animals, leading to tissue response measurement. The method allows researchers to assess inflammation by monitoring granuloma formation and weight over time, making it a valuable model for studying anti-inflammatory properties in research settings. It effectively simulates chronic inflammatory conditions, providing insights into potential therapeutic effects.
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The concept of Cotton pellet granuloma in scientific sources
Cotton pellet granuloma is an experimental model for assessing chronic inflammation in rodents, achieved by implanting cotton pellets and monitoring the subsequent tissue response as a method of evaluating inflammatory processes.
(1) A model used to induce inflammation in experimental animals, where cotton pellets are implanted subcutaneously to study anti-inflammatory effects.[1] (2) A model for assessing anti-inflammatory properties by tracking the weight of granuloma formed due to cotton pellets implanted under the skin of experimental animals.[2] (3) An experimental method to assess chronic inflammation by implanting a sterile cotton pellet and measuring resultant tissue response.[3]
(1) A method employed to assess the efficacy of anti-inflammatory agents based on granuloma tissue formation induced by implanted cotton pellets.[4] (2) An experimental model used to evaluate chronic inflammatory responses by implanting cotton pellets in laboratory animals.[5] (3) A method to evaluate chronic inflammation by inserting a cotton pellet under the skin of rodents and measuring the resultant tissue response.[6]
(1) A model of chronic inflammation in which cotton pellets are implanted in rats to study granuloma formation and assess anti-inflammatory treatments.[7]