Significance of Coagulase negative Staphylococci
Coagulase negative Staphylococci (CoNS) are a group of bacteria known for their association with late-onset sepsis in very low birthweight infants and as significant nosocomial pathogens. While they do not produce the coagulase enzyme and are often considered less virulent, CoNS can lead to serious infections, particularly in patients with indwelling medical devices or immune-compromised individuals. These bacteria are prevalent in hospital environments and play a notable role in healthcare-associated infections.
Synonyms: Staphylococcus epidermidis, Staphylococcus saprophyticus, Staphylococcus haemolyticus
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The concept of Coagulase negative Staphylococci in scientific sources
Coagulase negative Staphylococci are aerobic bacteria commonly found in vaginal flora and the most frequently isolated in studies. They consist of various staphylococcus species lacking coagulase production, often linked to infections in immune-compromised individuals.
From: World Journal of Pharmaceutical Research
(1) Bacteria commonly associated with late-onset sepsis in very low birthweight infants, often acquired through the hospital environment.[1] (2) A group of Staphylococci that do not produce coagulase enzyme and are often less virulent but can cause infections.[2] (3) are a group of bacteria identified as significant nosocomial pathogens associated with infections, particularly in patients with indwelling medical devices.[3] (4) A group of staphylococcus species that do not produce coagulase and are often associated with infections, especially in immune-compromised individuals.[4] (5) A group of aerobic bacteria prevalent in the vaginal flora, identified as the most commonly isolated aerobic organisms in the study.[5]
From: The Malaysian Journal of Medical Sciences
(1) CoNS are considered low pathogenic organisms but have been recognized as significant nosocomial pathogens that can cause serious infections.[6]