Significance of Clinical studies
Clinical studies are research investigations conducted with human participants to evaluate the safety and effectiveness of medical interventions. These studies span various fields, including Ayurveda, psychiatry, health sciences, and environmental sciences. They assess treatments for conditions like diabetes, anxiety, cancer, and COVID-19. These studies validate traditional practices, explore new therapies, and require rigorous methodology to establish evidence-based data. Further research is often needed to confirm findings and expand the scope of potential treatments.
Synonyms: Clinical trials, Medical research, Clinical research, Biomedical studies, Patient studies, Health research, Human testing, Healthcare studies
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Clinical studies'
In Hinduism, clinical studies involve evaluating treatments (Ayurvedic herbs, therapies) on human participants. These studies aim to validate safety, effectiveness, and traditional uses, while integrating ancient knowledge with modern science.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Clinical studies are needed to demonstrate the efficacy of Bhasma, and official guidelines must be set regarding standardization, toxicity, safety, mass production, and labeling.[1] (2) Compilation of case reports and clinical studies is needed to standardize the treatment protocol and define outcome measures, ensuring consistent and effective application of Kshara Karma.[2] (3) These are research investigations conducted on human subjects to evaluate the safety and efficacy of medical interventions.[3] (4) These are needed to validate the therapeutic utility of Arka Taila, especially considering its wide range of phytochemical components, requiring larger sample sizes.[4] (5) Standardized protocols and comparative studies with contemporary pain management techniques could firmly establish Viddhagnikarma’s place within mainstream pain management.[5]
From: International Research Journal of Ayurveda and Yoga
(1) These demonstrate pranayama's efficacy in conditions such as hypertension, cardiac arrhythmias, and diabetes.[6] (2) Further research and these are warranted to validate these findings and broaden the scope of Ayurvedic therapies.[7] (3) A plethora of these have been done to create evidence-based data at various Ayurveda postgraduate institutions and research organizations.[8] (4) Research investigations conducted on human subjects to assess the effects and outcomes of a particular treatment or intervention. They are used to evaluate Shirodhara.[9] (5) Have validated zinc supplementation in delaying the progression of AMD.[10]
From: Journal of Ayurvedic and Herbal Medicine
(1) In 2001, the first Traditional Chinese Medicine (TCM), Kanglaite, was approved by the FDA for phase 1 for the treatment of cancer.[11] (2) These are investigations designed to evaluate the safety and effectiveness of medical interventions, in this case, herbal medicine, to help reduce the risk of infection by boosting our immunity.[12] (3) Clinical studies are research endeavors that systematically investigate health-related issues, contributing to evidence-based approaches and the advancement of medical knowledge, as mentioned in the context of Ayurvedic practices and the need for comprehensive research.[13] (4) This term refers to the investigations done in the field of medicine, and the drug possesses various properties based on the experimental and clinical studies.[14] (5) These are medical research studies conducted on human participants to assess the safety and effectiveness of a treatment, such as the use of Hygrophila auriculata.[15]
The concept of Clinical studies in scientific sources
Clinical studies involve research with human participants to evaluate the safety and effectiveness of medical treatments, interventions, or drugs, often in real-world healthcare settings.
From: Asian Journal of Pharmaceutics
(1) Clinical studies evaluate these formulations’ performance, pharmacokinetics, and therapeutic outcomes in humans, paving the way for commercialization.[16] (2) These studies have revealed the significant role of celecoxib for inducing anticarcinogenic effects on various colon cancer cell lines.[17] (3) The article does not contain this type of study or patient’s data, and authors are accountable for the aspects of work.[18] (4) These studies are required to confirm better product development, along with preclinical studies.[19] (5) It may become impractical to address the changes in formulation strategy using both resource and time-intensive ones in patients.[20]
From: International Journal of Pharmacology
(1) The nature of toxic insults inflicted upon the animals subjected to oral administration of different doses of Melastoma leaf extract provided valuable reference tool for future clinical studies.[21] (2) It refers to investigations of the therapeutic efficacies of camel urine, such as treating diabetic neuropathy in Asian countries.[22] (3) Clinical studies are needed to highlight the behavioral effects of all groups of antibiotics and to identify their production mechanisms for better use of antibiotics.[23] (4) Clinical studies on the efficacy, safety and dosage of favipiravir have recently intensified due to the recognition of serious side effects when high doses of favipiravir are administered.[24] (5) At present, many clinical studies on ApoB/ApoA1, CRP, LPS and AP mainly analyze the relationship with the degree of disease.[25]
From: The Malaysian Journal of Medical Sciences
(1) Retrieved data from these reports and surveillance have stated that the patients on hemodialysis are vulnerable to catheter related infections.[26] (2) Clinical studies have suggested that there is a close relationship of hypothalamic–pituitary–ovarian axis (HPO) with hypothalamic–pituitary–thyroid axis (HPT).[27] (3) Clinical studies are needed to test the effectiveness of (R)-(−)-carvone in treating hyperlipidaemia and to test its effects on insulin release in humans.[28] (4) These are studies that interact with techniques used in cognitive neurosciences in a transdisciplinary manner, offering a comprehensive understanding.[29] (5) The IGF1R-targeted agents that have been used in pre-clinical and/or these studies are: the small-molecule inhibitors linsitinib (OSI-906), BMS-754807, AXL1717, and XL228 and others.[30]
From: South African Family Practice
(1) These are research investigations into medical treatments, and a systematic review found high sensitivity and specificity of ultrasound in these studies.[31] (2) These are research investigations that evaluate the safety and efficacy of medical interventions, and they are a crucial part of medical progress.[32] (3) The text indicates research investigations conducted on human participants to evaluate the safety and efficacy of medical interventions, such as drug therapies.[33] (4) This refers to the research conducted to evaluate the effects of the CHD-FA wellness drink, and its outcomes were assessed in the context of the HIV-1 positive subjects.[34] (5) These are research investigations that involve human participants, and are used to evaluate the effects of statins.[35]
From: South African Journal of Physiotherapy
(1) When interrogating some of these that have overall shown no benefit of airway clearance therapy, it is interesting that there is usually a subgroup of patients who clearly derive benefit.[36] (2) These require sample size tables to be properly conducted and have accurate results.[37] (3) These are research studies that involve human participants, and the findings can be used to improve patient care.[38] (4) Other topics are related to research and clinical studies, for example, a diagnostically based sensory motor programme in Subnormal School showed significant gains.[39] (5) Investigations that assess the impact of interventions on patient outcomes, and have shown improvement in motor functions after using electrical stimulation.[40]
From: South African Journal of HIV Medicine
(1) Well-planned studies in this area are urgently needed to supplement the sparse data currently available in the southern African situation.[41] (2) This refers to research conducted to evaluate the safety and effectiveness of medical interventions or diagnostic tests, which informs medical practice.[42] (3) These are studies conducted to evaluate the safety and efficacy of a drug, and decisions about dosing were based upon manufacturers’ information, ARV formulation choices, and available data from these, and there are no reported pharmacokinetic or these studies directly comparing weight band with mg/kg or BSA dosing approaches.[43] (4) These are research investigations involving patients, which the study's findings are relevant to.[44] (5) These are studies that are conducted to test the safety and effectiveness of a treatment, and these studies were discontinued prematurely with the African potato.[45]
From: Journal of Public Health in Africa
(1) FARMOVS has a track record of over 3,000 successful endeavors, indicating its proficiency in conducting research on the African continent, contributing to the development of innovative interventions.[46] (2) Clinical studies are research investigations conducted in a clinical setting to evaluate health interventions or examine health-related outcomes, and BMI is used in these studies.[47] (3) These studies among SARS-CoV-2 infected patients have shown that the cytokine storm is the principal cause of severe morbidity, poor prognosis, and mortality due to COVID-19.[48]
From: Journal of Medicinal Plants for Economic Development
(1) Many species reportedly used for medicine lack recorded evidence or data on clinical studies.[49] (2) Further preclinical and these are needed to validate the efficacy of withaferin A against specific cancer types and to determine optimal treatment regimens and potential side effects.[50]
From: Onderstepoort Journal of Veterinary Research
(1) This involves the investigation of diseases and their effects on patients, which is important for improving awareness among clinicians.[51]
From: African Journal of Primary Health Care and Family Medicine
(1) Clinical studies are research investigations that involve human participants, and the text references various clinical studies that have examined the effectiveness of disulfiram in the treatment of alcoholism.[52]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) It involves research conducted on human participants to evaluate medical interventions, which are enhanced by data-driven scientific research.[53] (2) These have confirmed the effectiveness of tele-visits programs, which support psychological development and rehabilitation.[54] (3) In patients with VTE, a series of clinical studies addressed the role of sporadic mutations and polymorphisms in the TM gene.[55] (4) Are research investigations involving human participants, and there is a need for more of these to guarantee the safety of newborns.[56] (5) These are needed to assess stem cells in general and oral mucosa stem cells in particular for diabetic wound healing treatment, representing a crucial step.[57]
From: Sustainability Journal (MDPI)
(1) The design of the indicators was achieved by collecting the most advanced practices of representative healthcare facilities from all over the world, which were confirmed in recent research.[58]
From: South African Journal of Psychiatry
(1) These studies investigate risperidone induced hyperprolactinemia from basic to clinical perspectives.[59] (2) These studies are the aim of providing an overview of research into social phobia, which is relevant to future clinical studies, as mentioned in the text.[60] (3) These are investigations that concern the applications of brain imaging in psychiatry, and for the most part, they have been limited to the use of structural imaging, and they have specific applications.[61] (4) These are research investigations that involve human participants, designed to evaluate the effectiveness of medical treatments.[62] (5) These are investigations, as the text indicates, that have demonstrated HPG dysfunction among some men suffering from depressive disorders.[63]
From: International Journal of Pharmacology
(1) Clinical studies were noted as a missing component for validating the experimental findings regarding picroside's role in fat synthesis.[64] (2) Clinical studies are suggested as a necessary next step to confirm the anti-anxiety effects of Lagenaria sicereria in humans and to determine its applicability for treating anxiety disorders.[65]
From: Religions Journal (MDPI)
(1) Clinical Studies are research investigations conducted in healthcare settings to evaluate the effects of interventions or to understand phenomena, such as post-bereavement hallucinatory experiences.[66]