Significance of Clinical manifestation
Clinical manifestation refers to the observable signs and symptoms of a disease. These manifestations are essential for diagnosis, assessment, and treatment planning across various medical fields. The presentation of these signs and symptoms can vary widely, ranging from mild to severe, and can include physical signs, such as joint pain, swelling, and fever, and also internal signs, like the effects of drug-induced syndromes or the presentation of a disease, like psychosis.
Synonyms: Clinical presentation, Symptoms, Disease presentation, Symptom, Sign, Indication, Presentation, Expression, Evidence
In Dutch: Klinische manifestatie; In Finnish: Kliininen ilmentymä; In Spanish: Manifestación clínica
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Clinical manifestation'
In Hinduism, clinical manifestation describes observable signs and symptoms of illness, crucial for diagnosis and treatment. It varies based on the doshas, affected tissues, and causative agents, mirroring concepts like Kamala and Vatarakta. Understanding these manifestations guides appropriate therapeutic approaches, as detailed in Ayurvedic texts.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) This of a specific disease varies from mild menstrual irregularities to severe reproductive and metabolic dysfunction.[1] (2) Clinical manifestation of morbidity of Vata included the different clinical manifestation according to the site of involvement, according to the study.[2] (3) This refers to the symptoms and signs of typhoid, such as fever and headache, which were used to select patients for the observational study.[3] (4) Clinical manifestations like Psoriatic arthritis, Psoriatic Pustules and psoriatic erythroderma as well as some cases of psoriasis palmoplantaris and inverse psoriasis are to be considered as severe.[4] (5) Clinical manifestations of Tinea pedis include erythema, edema, scaling, and pruritus, primarily affecting the web space between the fourth and fifth toes, which highlights the diverse presentations of dermatophytosis.[5]
From: International Research Journal of Ayurveda and Yoga
(1) Authentic knowledge about clinical manifestation of disease is important for royal physician.[6] (2) The presentation of Vicharchika, which is frequently linked to eczema and compared to it by modern dermatology.[7] (3) Immunity is the main factor that helps to prevent this of the virus to a great extent.[8] (4) The observable signs and symptoms of poisoning, explored in Agada Tantra.[9] (5) Aspects of Gridhrasi told in Ayurvedic classics that can be well equated with Sciatica which is well explained in modern medicine.[10]
From: Journal of Ayurvedic and Herbal Medicine
(1) It is the basis for diagnoses in the study, particularly for acute mucopurulent and hemorrhagic conjunctivitis, and for inferring bacterial or viral involvement.[11] (2) Clinical manifestation varies for each and every mycotoxins and their doses, depending on the dhaatus and doshas affected, and food borne illnesses, including mycotoxins, are presented typically with gastrointestinal symptoms.[12] (3) These are the observable signs and reported symptoms that are used to diagnose and assess the severity of the eye condition being studied, which is also known as Netrabhishyanda.[13] (4) These are the shwasakricchta (dyspnoea), kasa (cough), ghurghurahat (wheezing sound) and difficulty in breathing, especially on lying position, which are presented.[14] (5) This describes the observable signs and symptoms of a disease, such as gouty arthritis, urolithiasis, and renal dysfunction.[15]
From: History of Indian Medicine (and Ayurveda)
(1) Physical signs and symptoms that arise when one or more of the Triumvirate are out of balance, affecting the integrity of the body.[16] (2) Physical signs and symptoms that arise from the pathological states of the Triumvirate organizations.[17]
The concept of Clinical manifestation in scientific sources
Clinical manifestation refers to the observable signs and symptoms of a disease or condition. These are visible, measurable effects, varying across conditions like Parkinson's or Zika virus. They are crucial for diagnosis, assessment, and understanding disease progression.
From: The Malaysian Journal of Medical Sciences
(1) These are the signs and symptoms of a disease, and it was noted that malaria can have similar manifestations to other systemic infections, potentially leading to misdiagnosis.[18] (2) These are the observable signs and symptoms of a disease, which need to be considered when assessing patients for DBS.[19] (3) These are the various symptoms and signs that a patient with a pheochromocytoma might experience, which are variable and can resemble other diseases.[20] (4) These are the signs and symptoms of a disease, and the study analyzed the association between specific manifestations and antibiotic prescriptions.[21] (5) Clinical manifestations of the illness vary, ranging from asymptomatic infection to severe forms of the disease.[22]
From: Asian Journal of Pharmaceutics
(1) Even in the absence of these signs of pyelonephritis, therapy for chronic systemic inflammation should be recommended.[23] (2) Cross-linkage can lead to various of these associated with aging.[24] (3) Aspects that are focused on in the presentation of orofacial granulomatosis and pyostomatitis vegetans, along with diagnostic criteria and common management approaches toward patients diagnosed with Crohn's disease.[25] (4) Signs and symptoms observed among the studied patients, such as general weakness, headache, and dizziness.[26] (5) The dynamics of these of liver cirrhosis was studied to assess treatment results.[27]
From: South African Family Practice
(1) Seizures are the of an electrical “surge” which is cerebral in origin and can be broadly characterised as motor and non-motor.[28] (2) Clinical manifestations of HeFH versus HoFH include tendon xanthomas, cutaneous xanthoma, and coronary disease, with varying LDL cholesterol levels and age of onset.[29] (3) Symptoms and signs associated with irritable bowel syndrome, which may overlap with functional dyspepsia and include heartburn, nausea, vomiting, and early satiety.[30] (4) FPIES can further be classified according to the timing of symptoms (acute vs. chronic FPIES), the severity of these (mild, moderate and severe), age of onset (early-onset, late-onset, adult FPIES), type of food triggers (cow’s milk/soy vs. solid foods) and the presence of food-specific IgE (sIgE) (atypical FPIES).[31] (5) Signs and symptoms of pyogenic liver abscess, often distinct from those of other cystic lesions of the liver.[32]
From: International Journal of Pharmacology
(1) Clinical manifestations of ulcerative colitis can be mimicked by oxazolone induction, which is considered the ideal model for studying the disease.[33] (2) Clinical manifestations are a part of myocardial ischemia/reperfusion injury.[34] (3) It of cardiac failure varies depending on the dosage and duration of consumption of AlP in patients.[35] (4) These include long-term repeated cough, wheezing, and chest tightness that are associated with a long disease course.[36] (5) CHM has been extensively applied to ameliorate these and has achieved gratifying efficacy through diverse prescriptions.[37]
From: South African Journal of HIV Medicine
(1) As children are growing and developing, many of these may be unique to children.[38] (2) Prevalence and clinical manifestations of disseminated mycobacterium avium complex infection are discussed.[39] (3) The signs and symptoms that characterize a particular disease, studied here in relation to TB in young children on ART.[40] (4) These are the observable signs and symptoms of a disease, and the effect of HIV viraemia and associated immunological changes on the clinical manifestations of COVID-19 remain poorly described.[41] (5) These are the observable signs and symptoms of a disease, which were seen more often in patients who were HIV-positive in the study.[42]
From: Onderstepoort Journal of Veterinary Research
(1) The disease in ruminant livestock, especially sheep and cattle, are characterised by high mortality and high abortion rates particularly in infected pregnant animals.[43] (2) These are the observable signs and symptoms of a disease, and infected cats may exhibit these, including depression, anorexia, and fever, which can lead to more severe issues.[44] (3) These are the observable symptoms of the disease, which were similar in Friesians, Borans, and non-endemic Zebus, but different in the endemic Zebus.[45] (4) Clinical manifestation refers to the observable signs and symptoms of a disease, which were similar to those described in other studies.[46] (5) The predominant clinical manifestations encountered were due to gastrointestinal helminth infection and intoxications attributed to plant poisoning.[47]
From: African Journal of Primary Health Care and Family Medicine
(1) The diagnosis of scurvy can be made when there are these consistent with vitamin C deficiency, alongside a history of inadequate dietary intake, according to the text.[48] (2) In Kinshasa, it was found that patients with hypertension had little knowledge of their condition in terms of risk factors, clinical manifestations and complications, which was a factor in the study.[49] (3) These are the observable signs and symptoms of interactions between herbal and conventional drugs, and are used to study their interactions.[50] (4) These are the observable signs and symptoms of a disease, which are considered in the study of HIV and parasite co-infections.[51] (5) Clinical manifestations were one of the specific areas where respondents scored poorly, indicating limited knowledge and misinterpretations of the signs and symptoms of diabetes.[52]
From: Journal of Public Health in Africa
(1) Clinical manifestations of Ebola include fever, severe diarrhea, and vomiting, differing from previous outbreaks, with rapid progression to multi-systemic involvement, potentially mimicking other common infectious diseases, leading to misdiagnosis and management challenges.[53] (2) Clinical manifestations and complications require expert collaboration to refine case classification criteria for more precise treatment, which is essential to treat the disease.[54] (3) The most common clinical manifestations were palpitations, dizziness, shortness of breath, and cramping and shaking in each hand after receiving the vaccine.[55] (4) This is the signs and symptoms that a person experiences when they have measles, such as fever and rash.[56] (5) This term refers to the observable signs and symptoms of a disease, and it is mentioned in the study in relation to the development of cardiovascular diseases.[57]
From: South African Journal of Physiotherapy
(1) These vary in terms of pattern and may present in acute, sub-acute or commonly chronic forms, as mentioned in the text.[58] (2) The chief symptoms are pain, stiffness and soreness, and the usual signs are tenderness and perhaps some limitation of movement.[59]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) "Clinical manifestations", outcomes, and management of delirium in critical illness are discussed by Stollings, J.L., Kotfis, K., Chanques, G., Pun, B.T., Pandharipande, P.P., and Ely, E.W., providing insights into this condition.[60] (2) Upon contact of the skin with the jellyfish, pain of variable intensity is the most frequent and often the only clinical manifestation of the envenomation, with a vesiculourticarial eruption possibly resembling the shape of the tentacles.[61] (3) These are the observable signs and symptoms of a disease or condition.[62] (4) Clinical manifestations are the observable signs and symptoms of a disease, and the patient with LRBA deficiency exhibited a wide spectrum of clinical manifestations, including diabetes, arthritis, diarrhea, and growth failure.[63] (5) The Ghent criteria include clinical manifestations defined as major and minor involving several systems, such as the skeletal, ocular, cardiovascular, and pulmonary systems.[64]
From: International Journal of Pharmacology
(1) These are the observable effects of nRTI-related mitochondrial toxicity, which can resemble symptoms of inherited mitochondrial diseases.[65] (2) The observable signs and symptoms of a disease.[66] (3) Observed clinical signs in the goats included profuse salivation, bleating, neck flexing, and polyuria.[67]
From: South African Journal of Psychiatry
(1) The signs and symptoms of a disease, such as muscle weakness and fatigue in myasthenia gravis.[68] (2) These are the specific ways the disease shows itself, as highlighted in the case, and emphasize the need for collaboration between neurologists and psychiatrists in management.[69]