Significance of Clearance
Clearance refers to the volume of plasma from which a substance is entirely removed per unit time. This concept is significant in pharmacology, as it helps in understanding the elimination of drugs from the body. By measuring clearance, researchers can assess how effectively a substance is cleared from the bloodstream, which ultimately aids in determining appropriate dosing and timing for drug administration. Understanding clearance is crucial for optimizing therapeutic effects and minimizing toxicity in patients.
Synonyms: Authorization, Permission, Sanction, Approval, Consent, Validation, Release., Discount, Reduction
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The concept of Clearance in scientific sources
Clearance is the measure of the plasma volume from which a substance is entirely removed over time, crucial for comprehending the drug elimination process in pharmacokinetics.
From: World Journal of Pharmaceutical Research
(1) The volume of plasma from which a substance is completely removed per unit time, important for understanding drug elimination.[1]