Significance of Chemical screening
Chemical screening refers to a systematic approach for identifying and analyzing the presence of various chemical compounds in plant extracts and assessing their biological activities, particularly in the context of medicinal properties. This process is crucial in drug discovery, as it helps evaluate the therapeutic potential of natural compounds by determining their specific components, such as alkaloids and flavonoids, and their effectiveness against diseases. Techniques and analyses conducted during chemical screening aim to ascertain the compatibility of these compounds with established medicinal standards.
Synonyms: Chemical analysis, Chemical testing, Compound screening, Chemical profiling, Molecular screening, Drug screening, Pharmacological screening, High-throughput screening, Biochemical screening, Library screening.
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The concept of Chemical screening in scientific sources
Chemical screening is an initial analytical process used to detect chemical substances in plant extracts, serving as a crucial first step in drug discovery to identify novel compounds with potential therapeutic benefits.
(1) A process used to identify the various active compounds present in Butea monosperma, including flavonoids and fatty acids.[1] (2) A systematic approach to identify and analyze the chemical compounds in various biological entities.[2] (3) The assessment of compounds for specific biological activities or properties, critical in drug discovery.[3] (4) A systematic approach used to determine the presence of various compounds and their activities in the crude extracts.[4] (5) An analytical procedure to identify the presence of various chemical compounds within a substance, such as alkaloids, terpenoids, and flavonoids in the ethanolic extract.[5]
(1) The process of analyzing the chemical properties of medicinal plants to ascertain their medicinal qualities and compatibility with Indian Pharmacopeial standards.[6] (2) The process of testing plant specimens to identify their active principles before making conclusions about their medicinal uses.[7] (3) The process of testing plant extracts for their chemical properties and potential medicinal effects.[8]
(1) An initial step in drug discovery that involves evaluating plant extracts to identify novel compounds with potential therapeutic effects.[9]