Significance of Central nervous system depressant activity
Central nervous system depressant activity encompasses various effects of certain plant extracts and compounds that can lead to sedation and reduced brain activity. For instance, extracts of Tragia plukenetii and Pergularia daemia show potential sedative properties through decreased locomotor activity in animal studies. Similarly, Basella alba demonstrates possible relaxation effects. Overall, this activity involves a reduction in exploratory capacity and increased sleep duration, highlighting the importance of these substances in understanding sedative effects on the central nervous system.
Synonyms: Cns depressant activity, Tranquilizing properties, Relaxant activity, Sedative, Cns depressant
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The concept of Central nervous system depressant activity in scientific sources
Central nervous system depressant activity involves extracts from Tragia plukenetii and Pergularia daemia, both demonstrating sedative effects, which reduce exploratory behavior and locomotor function, as observed in scientific studies involving mice.
From: World Journal of Pharmaceutical Research
(1) The ability of a substance to reduce brain activity, often resulting in sedation.[1] (2) Testing behavioral effects of the synthesized compounds on the central nervous system by measuring locomotion in animals.[2] (3) The effect of a compound that suppresses the activity of the central nervous system, potentially increasing sleep duration.[3] (4) The effect of Basella alba on the central nervous system, possibly leading to relaxation or sedation.[4] (5) The effect of Pergularia daemia extracts that can induce sedation, evaluated through studies on mice.[5]
From: AYU (Journal of Research in Ayurveda)
(1) The observed effects of Tragia plukenetii's extracts that lead to a reduction in exploratory capacity and locomotor activity, indicating potential sedative properties.[6]