Significance of Cell viability test
Cell viability test refers to an assay designed to evaluate the living status of cells after exposure to toxic substances and treatments. It functions as an experimental procedure to assess both the health and reproductive capacity of cells following treatment with various inhibitors. Additionally, this test measures the number of viable cells in a culture, which is often crucial for assessing the effects of treatments on cancer cells.
Synonyms: Cell survival assay, Cell viability assay, Viability test, Cytotoxicity test, Cytotoxicity test.
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The concept of Cell viability test in scientific sources
Cell viability test is an experimental procedure used to evaluate the health and reproductive capacity of cells, particularly after exposure to different inhibitors, providing crucial insights into cellular responses to treatments.
From: International Journal of Pharmacology
(1) The MTS test is used to determine cell viability and proliferation and is based on the conversion of tetrazolium salt into a coloured structure as a result of mitochondrial activities.[1] (2) The viability of cells was assessed by MTT assay (Mosmann, 1983) using MCF-7 cell lines, indicating a method for assessing cell health.[2] (3) A cell viability test, employing the MTT assay, was conducted to determine the impact of Zeylenone on the survival of HCT116 cells at various concentrations.[3] (4) An assay, such as the MTT assay, used to determine the number of living cells in a culture after treatment.[4] (5) Cell viability tests, such as the MTT assay, are performed to estimate the protective effects of nattokinase against Aβ25-35 induced cell death.[5]