Significance of Cell viability
Cell viability, across various fields, consistently signifies the ability of cells to survive and function. It is a crucial metric, often measured as a percentage, to assess the impact of treatments or substances on cell health. Assays like MTT, CCK-8, and Trypan blue exclusion are frequently employed to quantify the number of living cells, reflecting their survival and overall health under different conditions. Cell viability plays a critical role in understanding treatment effects, determining toxicity, and evaluating the efficacy of various compounds.
Synonyms: Cell survival, Cell health, Cellular viability, Cell proliferation, Cell life., Cellular viability.
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Cell viability'
In Hinduism, cell viability signifies a cell's capacity to live and operate, crucial for assessing substances' impact on cells. It's a key metric in inflammation studies, cancer research, and evaluating treatments like ghee and herbal extracts.
From: Journal of Ayurvedic and Herbal Medicine
(1) This is a measure of the number of cells that are alive in a population. Recent studies have shown that (-)-epigallocatechin-3-gallate (EGCG) is able to down regulate the expression of telomerase and leading to the suppressed this of the breast cancer cell line (MCF-7).[1] (2) This is a measure used in the MTT assay to determine the effectiveness of CBD and THC extracts, indicating the number of living prostate cancer cells after treatment.[2] (3) This refers to the ability of cells to survive and function, and it was assessed in the study to determine the effects of Karpa Chenthur on both cancer and normal cells.[3] (4) Cell viability, the ability of cells to function and survive, decreases at a 30μM curcumin concentration in Vero cells infected with the dengue virus.[4] (5) This describes the proportion of cells in a population that are alive and functioning normally, which is an important measure in cell-based assays.[5]
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Cell viability is a factor evaluated in the study, showing a nonsignificant difference in the cell viability of the PBCM after treatment with ghee of buffalo, while moderate toxicity was observed with Terminalia arjuna extracts treatment at higher concentrations.[6] (2) The ability of cells to survive and function, which is used to measure the inhibitory properties of the polyherbal formulation against inflammation.[7] (3) This is the ability of cells to survive and function, and is often measured in experiments to assess the effectiveness of substances like Amrutham Ghrita on cancer cells.[8] (4) This is a measure of the health and functionality of cells, and the effects of Calotropis procera on cell viability are studied in cancer research.[9]
The concept of Cell viability in scientific sources
Cell viability is the measure of a cell's ability to survive and function. It is assessed by the proportion of live, healthy cells within a sample, often measured after treatment with substances. This assessment helps determine the cytotoxic effects of treatments on various cell types.
From: International Journal of Pharmacology
(1) Cell viability is a measure of the number of living cells in a population, often assessed using assays such as the Cell Counting Kit-8 (CCK-8).[10] (2) Cell viability is the measure of the number of live cells in a population, and it is assessed in lung cancer cell lines treated with Genistein and Cisplatin to determine the drug's effect.[11] (3) The experiment showed that co-administration of cisplatin with tempol increased apoptotic proteins and decreased 'cell viability' more than administration of cisplatin and tempol alone.[12]
From: The Malaysian Journal of Medical Sciences
(1) Cell viability was evaluated using MTT assay, with the cellular viability at day 1 used as an indicator of the efficiency of human dermal fibroblasts attachment.[13] (2) This refers to the ability of cells to survive and function, which was measured using the MTT assay in the study.[14] (3) This is a crucial factor in assessing the impact of different purification methods and the effects of toxins on lymphocytes, as highlighted in the text.[15]
From: Asian Journal of Pharmaceutics
(1) MTT is reduced to blue formazan product by mitochondrial dehydrogenase, which reflects proper mitochondrial function and cell viability.[16] (2) It refers to the viability of AFB treated cells which decreased while the toxin concentration increased during the cytotoxic effect.[17] (3) The measure of the number of living cells in a population, assessed after exposure to plant extracts at varying concentrations.[18]
From: Onderstepoort Journal of Veterinary Research
(1) The ability of cells to survive and function, measured using the MTT assay to determine the toxicity of the plant extracts.[19] (2) This refers to the ability of cells to survive and function normally, assessed in toxicity tests.[20]
From: South African Journal of Physiotherapy
(1) The state of being alive and functioning for cells, which was measured using the MTT assay to assess the effects of laser treatment on fibroblast activity and proliferation within the cell culture.[21]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) While NO 2 can induce cytokine release, its effect on the viability of bronchial epithelial cells is minimal at certain concentrations.[22] (2) A significant negative correlation was observed between cell viability and LDH leakage, meaning that as cell viability decreased, LDH leakage increased, which was consistent with MTT results indicating increased cell ruptures and deaths.[23] (3) A quantitative measure reflecting the proportion of living cells remaining after a period of exposure to a potentially harmful agent, which was found to decrease in a concentration-dependent manner.[24]
From: Sustainability Journal (MDPI)
(1) The measure of living cells within a population, which can be negatively impacted by the toxic effects of micro- and nanoplastics on microalgae.[25] (2) Cell viability refers to the percentage of living cells remaining after exposure to a substance, assessed using the SRB assay to determine the safety profile of the synthesized nanoparticles on HSF cells.[26] (3) Cell viability refers to the state of a cell being alive and healthy, and its measurement is crucial for assessing the impact of environmental factors or treatments on microbial populations.[27]
From: International Journal of Pharmacology
(1) This refers to the ability of cells to survive and function, and the highest rate of this was observed in the control group, while the lowest was in the TCZ-treated group.[28] (2) This is a measure of the health and function of cells, which was suppressed by benzoximemethyl amine in HCT15 and DLD-1 cells.[29]
From: International Journal of Pharmacology
(1) The measure of living cells within a population, often assessed using assays like MTT to determine the impact of treatments.[30] (2) Cell viability refers to the health and survival of cells, which was assessed using the CCK-8 test in FAS-treated bone marrow mesenchymal stem cells.[31] (3) Cell viability refers to the state of living cells and was measured using MTT assay to assess the protective effects of nattokinase against Aβ-induced toxicity.[32]
From: South African Journal of Psychiatry
(1) Cell viability was assessed spectrophotometrically by Methyl-thiazolyl tetrazolium (MTT) salt reduction in the study investigating the relationship between corticosterone and neuron cell death.[33]