Significance of Cell proliferation
Cell proliferation refers to the process by which cells divide and multiply, a critical mechanism in biological systems and especially relevant in cancer biology. Inhibiting cell proliferation is a targeted effect of various therapeutic agents, particularly in treating cancers such as ER-positive breast cancer. This process is not only essential for normal tissue repair but also for understanding cancer growth and treatment effects, making it a focal point in numerous biomedical studies and therapeutic interventions.
Synonyms: Cell growth, Cell division, Cell expansion, Cell multiplication, Mitotic activity, Cellular proliferation
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The concept of Cell proliferation in scientific sources
Cell proliferation is the growth and division of cells, essential for evaluating the effects of chloroform extract in cytotoxicity assays, indicating its relevance in assessing cellular responses and potential toxicity.
(1) This is the process of cells multiplying, and loss of the p16 gene function may lead to cancer progression by allowing unregulated cellular proliferation.[1] (2) This was significantly enhanced by OTC-I scaffolds and the coated surface compared to the control, but no differences were observed between the scaffolds and coated surface.[2] (3) Cell proliferation is the process of cell division, and IGF1R promotes cell proliferation and survival, while a high plasma level of IGF1 is related to an increased risk of lung malignancy.[3] (4) Ang II mediates most of the biological effects of the renin-angiotensin system (RAS), such as vasoconstriction and this, via the AT1 receptor.[4] (5) This refers to the process of cells multiplying and is promoted by the cytokines released by UCMSCs, which is an effect of TRAIL with its agonistic/death receptors.[5]