Significance of Cell growth inhibition
Cell growth inhibition is the process of slowing or stopping cell proliferation, particularly in cancer cells. This effect can be achieved through various treatments or compounds, as demonstrated by studies. It is often a desired outcome in anti-cancer therapies, and is measured using assays to assess cell survival and proliferation. Several studies showcase this effect, including the impact of plant extracts, specific compounds, and treatments on different types of cancer cells.
Synonyms: Mitotic inhibition, Growth suppression, Proliferation inhibition, Anti-proliferative effect, Cytostatic effect
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The concept of Cell growth inhibition in scientific sources
Cell growth inhibition describes the slowing or stopping of cell proliferation, especially cancerous cells. This can be achieved through various treatments or compounds, as observed in studies involving wheatgrass, MEMPL, fluoroquinolones, medicinal plants, and other substances, resulting in reduced cell multiplication.
From: International Journal of Pharmacology
(1) Cell growth inhibition is the process by which the proliferation of cells is suppressed, a key effect observed in canine osteosarcoma cell lines treated with fluoroquinolones.[1] (2) This effect is exhibited by Fusarium tricinctum, an endophytic fungus that also demonstrates antioxidant activity.[2] (3) The reduction in the proliferation of cancer cells, measured as a percentage and calculated based on absorbance values from the MTT assay.[3]
From: The Malaysian Journal of Medical Sciences
(1) This is a mechanism by which vitexin exerts its anti-cancer action, achieved through the downregulation of specific signaling pathways, thereby preventing the uncontrolled proliferation of cancer cells.[4]
From: International Journal of Pharmacology
(1) The reduction in the proliferation of cells, observed in a dose-dependent manner with parameritannins A-2 and A-3.[5] (2) Cell growth inhibition studies showed that dichloromethane extract of the bark (TB2) had the highest anti-proliferative activity against MCF-7 cells.[6]