Significance of Cell death
Cell death is a biological process where cells undergo destruction or apoptosis, often evaluated in contexts like cancer treatment and disease. It can occur through various mechanisms, including programmed cell death, necrosis, and responses to oxidative damage and toxic insults. Factors such as proteins like Bad, inflammatory responses, and external agents like nanoparticles can trigger this process. Understanding cell death is crucial for developing therapeutic strategies against conditions like cancer and heart disease, where loss of cell viability can have significant implications.
Synonyms: Apoptosis, Necrosis, Cellular death, Programmed cell death, Cellular apoptosis, Pyknosis
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The concept of Cell death in scientific sources
Cell death encompasses the termination of cells through mechanisms like apoptosis, crucially impacting spermatogenic cells in newborn rats affected by methotrexate, and is a key consideration in evaluating cancer treatments.
From: The Malaysian Journal of Medical Sciences
(1) Cell death, specifically necrosis, was observed in the A549 cells treated with a particular Zamzam water preparation, indicating a potential mechanism of action against cancer cells.[1] (2) This is a fundamental biological process, and is studied in the context of mitochondrial DNA depletion in prostate epithelial cells, and is linked to anoikis resistance and invasion.[2] (3) Cell death is the main mechanism of cell death in UUO, which can be induced by tissue hypoxia, inflammatory mediator infiltration, and mechanical stress due to tubular dilatation.[3] (4) This is the process by which cells are eliminated, and this study evaluated the effect of tamarillo extracts on this process using cancer cell lines.[4] (5) This is the process by which cells cease to function and are eliminated from the body, either through programmed cell death or as a result of damage or injury.[5]