Significance of Cefotaxime
Cefotaxime is a third-generation cephalosporin antibiotic that plays a significant role in treating serious bacterial infections. It is often used as a control in studies examining the antibacterial effects of substances like neem leaf extracts, and is routinely tested for susceptibility in E. coli isolates, where resistance is a concern, particularly with ESBL-producing strains. Additionally, its effectiveness against Salmonella species and Pseudomonas aeruginosa infections underscores its importance in the ongoing challenge of antimicrobial resistance.
Synonyms: Claforan, Antibiotic, Cephalosporin, Beta-lactam, Antibacterial agent
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Cefotaxime in scientific sources
Cefotaxime is an antibiotic studied for treating Pseudomonas aeruginosa-infected wounds, assessed for efficacy with other treatments, and is a third-generation cephalosporin exhibiting low resistance in Salmonella species, though antimicrobial resistance remains a concern.
From: Asian Journal of Pharmaceutics
(1) An antibiotic that four isolates were resistant to, along with TMP-SMX, gentamycin, and ciprofloxacin.[1] (2) This is a cephalosporin antibiotic, it is used for treating a number of bacterial infections.[2] (3) This is one of the antibiotics tested for resistance in the study.[3] (4) A cephalosporine derivative that was loaded into phycocyanin nanoparticles in this study for improved antibacterial activity.[4]
From: Journal of Public Health in Africa
(1) This is an antibiotic, and the text provides information on the resistance rates of various bacteria to this antibiotic, including high resistance rates.[5]
From: Onderstepoort Journal of Veterinary Research
(1) Cefotaxime was another antimicrobial tested, and all isolates exhibited resistance, highlighting the widespread resistance observed in the study.[6]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Other like ceftriaxone, ampicillin and this can be considered as alternatives for penicillin when dealing with certain infections.[7]
From: Sustainability Journal (MDPI)
(1) This is an antibiotic that can be removed by a nanocomposite film made of NiFe2O4–COF–chitosan–terephthalaldehyde.[8]
From: International Journal of Pharmacology
(1) Cefotaxime is an antibiotic, specifically a third-generation cephalosporin, used in combination with pravastatin to treat septicaemic mice, significantly increasing their mean survival time and survivability.[9]