Significance of Carcinogenicity
Carcinogenicity refers to the property of a substance that indicates its potential to cause cancer. This assessment can be made through various evaluations, including the screening of potential drug candidates and reviewing occupational exposures to substances like cobalt. It encompasses several concerns, including the promotion of cancers such as lung and oral cancer by specific compounds. Additionally, it highlights the risks associated with non-compliant formulations and therapies, such as irinotecan, which may lead to acute leukemia through chromosomal changes.
Synonyms: Carcinogenic, Cancer risk, Carcinogenic potential, Tumorigenicity.
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Carcinogenicity in scientific sources
Carcinogenicity pertains to the potential of compounds such as furfural to induce cancer, emphasizing the importance of adherence to safety guidelines and its evaluation in drug candidate screening to assess cancer risk.
From: World Journal of Pharmaceutical Research
(1) The potential of a substance to cause cancer in living tissue.[1] (2) The potential of a substance, such as cobalt, to cause cancer in humans, particularly lung cancer in certain occupational settings.[2] (3) The property of certain substances, including components of betel quid, to promote cancer, particularly oral cancer.[3] (4) Refers to the potential link between irinotecan therapy and the development of acute leukemias associated with specific chromosomal changes.[4] (5) The property of a substance that indicates its potential to cause cancer, assessed for the compounds studied.[5]
From: AYU (Journal of Research in Ayurveda)
(1) The potential of certain compounds, like furfural, to cause cancer, which is a concern with formulations not adhering to established safety guidelines.[6]