Significance of Carcinogenesis
Carcinogenesis is the complex process by which normal cells transform into cancer cells, influenced by various genetic and environmental factors. This transformation can result from numerous influences, including oxidative stress, dietary factors, HPV infections, and chronic infections. The process encompasses multiple stages such as initiation, promotion, and progression, and can involve changes at the molecular level. Understanding carcinogenesis is crucial for examining applications in cancer research, treatment, and prevention strategies.
Synonyms: Cancer development, Tumorigenesis, Oncogenesis, Malignant transformation, Cancer formation, Neoplastic transformation
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The concept of Carcinogenesis in scientific sources
Carcinogenesis is the transformation of normal cells into cancer cells, influenced by genetic and environmental factors, highlighting the complex interplay in the development of cancer within individuals and populations.
From: The Malaysian Journal of Medical Sciences
(1) The process by which normal cells are transformed into cancer cells.[1] (2) The initiation of cancer formation, which may be influenced by various factors, including chronic infections like tuberculosis.[2]