Significance of C18 stationary phase

C18 stationary phase is a type of stationary phase used in liquid chromatography, designed to enhance resolution during the separation of compounds. This phase consists of long-chain hydrocarbon groups bonded to the silica particles used in the chromatography column, which improves the separation of both polar and non-polar substances. Its effectiveness makes it a popular choice for various analytical applications in scientific research and quality control in industries.

Synonyms: C18 column, Reverse phase chromatography

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The concept of C18 stationary phase in scientific sources

Science Books

C18 stationary phase is a critical component in liquid chromatography, enhancing separation resolution by providing a hydrophobic environment ideal for retaining non-polar compounds, thus improving the accuracy and effectiveness of analytical techniques.

Significance in Scientific journals, articles, etc.:

(1) A type of solid phase consisting of octadecylsilyl groups used in liquid chromatography for separating non-polar compounds.[1] (2) A type of stationary phase utilized in liquid chromatography for better resolution.[2]

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