Significance of Bio availability
Bio-availability refers to the degree and rate at which an active ingredient or moiety is absorbed and becomes available at the site of action following administration. It encompasses several aspects, including the efficiency of absorption into systemic circulation and utilization within the body. Factors like dosage form, such as mouth dissolving films, can potentially improve bio-availability. Understanding this concept is crucial, especially when evaluating drugs or therapeutic formulations and their effectiveness, as evidenced by examples like Metformin hydrochloride's absorption rate.
Synonyms: Bioavailability, Absorption efficiency, Biological availability, Drug absorption, Nutrient absorption, Pharmacological availability, Absorption, Assimilation, Accessibility
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Bio availability in scientific sources
Bioavailability refers to how effectively substances, including nutrients and drugs, are absorbed and utilized by the body. It's crucial for evaluating the efficacy of synthetic haematinic preparations and ensuring therapeutic formulations reach their active sites.
From: World Journal of Pharmaceutical Research
(1) The degree to which a substance becomes available to the target tissues after administration.[1] (2) The extent and rate at which the active ingredient or active moiety is absorbed and becomes available at the site of action.[2] (3) The extent and rate at which the active ingredient or active moiety is absorbed and becomes available at the site of action.[3] (4) The degree and rate at which a drug or active ingredient is absorbed and becomes available at the site of action, mentioned as low (60%) for Metformin hydrochloride.[4] (5) The extent and rate at which the active ingredient or active moiety is absorbed and becomes available at the site of action, potentially improved by mouth dissolving films.[5]
From: International Ayurvedic Medical Journal
(1) The degree and rate at which an administered drug or therapeutic formulation is absorbed and becomes available at the active site.[6]
From: Ancient Science of Life
(1) The degree and rate at which the active ingredient or active moiety of a drug or diet is absorbed and becomes available at the site of action.[7]