Significance of Bax protein
Bax protein is a pro-apoptotic member of the Bcl-2 family that plays a crucial role in regulating apoptosis. Research indicates that its expression significantly increases in response to cellular stress caused by aspartame. This suggests that Bax may be an important factor in understanding how certain substances can impact cell survival and death processes, highlighting its relevance in studies related to cellular stress responses and potential toxicological effects.
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The concept of Bax protein in scientific sources
Bax protein, a pro-apoptotic member of the Bcl-2 family, significantly increases in expression due to cellular stress caused by aspartame, highlighting its critical role in apoptosis and cellular response mechanisms.
From: World Journal of Pharmaceutical Research
(1) A pro-apoptotic member of the Bcl-2 family, whose expression increased markedly in response to aspartame-induced cellular stress.[1]
From: The Malaysian Journal of Medical Sciences
(1) A pro-apoptotic protein whose expression levels are higher in patients carrying the mtDNA 10398G variant, suggesting a role in apoptosis signaling in breast cancer.[2]