Significance of Bax protein
Synonyms: Bcl-2-associated x protein, Pro-apoptotic protein
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The concept of Bax protein in scientific sources
From: International Journal of Pharmacology
(1) This protein is a member of the Bcl-2 family and shows a structural peculiarity that promotes apoptosis, as stated in the text.[1] (2) These are proapoptotic, and can activate the release of cytochrome C, leading to cellular destruction.[2] (3) A protein whose expression is associated with pro-apoptotic events, with significant enhancement observed upon GA treatment compared to ALS.[3] (4) THSWD treatment down-regulated Bax protein expression, which is a pro-apoptotic protein.[4] (5) Bax protein level was suppressed by C.oil, and a marked decrease in its expression was observed in treatment groups with Chr-lip, indicating an anti-apoptotic effect.[5]
From: The Malaysian Journal of Medical Sciences
(1) This is a protein whose increase in levels was observed by flow cytometry, which further suggested the activation of the apoptotic pathway in cancer cells.[6] (2) A pro-apoptotic protein whose expression levels are higher in patients carrying the mtDNA 10398G variant, suggesting a role in apoptosis signaling in breast cancer.[7]
From: International Journal of Pharmacology
(1) A pro-apoptotic protein that promotes cell death, its expression is upregulated in cancer cells treated with obovatol.[8] (2) This protein promotes apoptosis; its expression was analyzed to understand how TBK1 influences the balance between cell survival and death.[9] (3) This protein is involved in apoptosis, and its expression in brain tissue is affected by ginsenoside Rg1 during cerebral ischemia.[10] (4) A protein that supports the initiation of apoptosis; its expression level was analyzed in stomach tissue to assess cellular damage.[11] (5) Bax protein is identified as a pro-apoptotic protein, and its levels were measured to assess the impact of treatments on programmed cell death.[12]