Significance of Atropine
Atropine, a crucial substance in various medical and scientific contexts, functions primarily as a muscarinic receptor antagonist. It is used in experiments to counteract decreased heart rates, block muscarinic receptors, and investigate the involvement of muscarinic pathways. Atropine also serves as a treatment for bradycardia, an antidote for organophosphorus poisoning, and a tool for studying the mechanisms of action of various substances. Additionally, it is employed in experiments to assess the effects of different extracts and drugs on various biological systems, as well as a standard material for the quantitative estimation of alkaloids.
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The concept of Atropine in scientific sources
Atropine is a versatile drug, functioning primarily as a muscarinic receptor antagonist. It's utilized in various medical and experimental contexts. It's employed to treat bradycardia, reverse neuromuscular block, and counter organophosphorus poisoning. Atropine is also used to investigate physiological mechanisms, like gut stimulation and blood pressure regulation.
From: International Journal of Pharmacology
(1) A medication that was administered intramuscularly to both groups of patients before undergoing gynaecological laparoscopic surgery under general anaesthesia.[1] (2) This is a medication administered in high doses to block cholinergic stimulation caused by organophosphate toxicity.[2] (3) Residual neuromuscular block was reversed with this drug.[3] (4) A medication administered intravenously, often with neostigmine, to counteract certain side effects of neuromuscular blockade reversal.[4] (5) A classical treatment modality employed for organophosphorus poisoning.[5]
From: The Malaysian Journal of Medical Sciences
(1) This may improve the symptoms when used in early resuscitation with 2-pralidoxime chloride, anticonvulsants, oxygen, respiratory support and fluids, according to the text.[6] (2) A muscarinic receptor antagonist used as a positive control in the study to compare the effects of F. asafoetida extract.[7]
From: Asian Journal of Pharmaceutics
(1) A pharmacological agent used to block parasympathetic effects, allowing the study of its influence on heart rate and blood volume.[8]
From: International Journal of Pharmacology
(1) Atropine is a substance used in experiments to block cholinergic activity and observe its effect on the gut stimulatory actions of T. chebula.[9] (2) A drug used to block muscarinic receptors, employed to investigate the mechanism of laxative effects.[10] (3) Atropine was administered with the anesthetic to help maintain heart rate and reduce secretions during surgery.[11] (4) A drug given to counteract a decrease in heart rate below a specified threshold during the procedure.[12] (5) Atropine was administered as a muscarinic antagonist in some experimental groups.[13]