Significance of Aspirin-induced ulcer
Aspirin-induced ulcer refers to gastric ulcers that develop as a result of administering aspirin, a common non-steroidal anti-inflammatory drug (NSAID). This phenomenon is often studied in rat models to evaluate the effectiveness of anti-ulcer treatments. The ulcers occur due to the damage aspirin inflicts on the gastric mucosa by inhibiting prostaglandins, which disrupt mucosal defenses and elevate gastric acid secretion. Fascinatingly, these experimental models help researchers understand the implications of aspirin usage on gastric health.
Synonyms: Gastrointestinal ulcer, Nsaid-induced ulcer, Peptic ulcer, Gastric ulcer, Stomach ulcer
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Aspirin-induced ulcer in scientific sources
Aspirin-induced ulcer denotes gastric ulcers arising from aspirin use, commonly observed in rat studies. In this context, it serves to assess the effectiveness of a methanolic extract in treating these ulcers.
From: World Journal of Pharmaceutical Research
(1) Gastric ulcers caused by the administration of aspirin, a non-steroidal anti-inflammatory drug (NSAID), which damages the gastric mucosa through inhibition of prostaglandins.[1] (2) A model of gastric ulcer created in rats through the administration of aspirin, used for testing the efficacy of anti-ulcer treatments.[2] (3) Aspirin induced ulcer refers to gastric ulcers caused by the use of aspirin, which can disrupt mucosal defenses and increase gastric acid secretion.[3] (4) Ulcers that occur as a side effect of aspirin use, often due to its effects on gastric mucosa.[4] (5) Ulcers that occur as a result of administering aspirin, a common NSAID, particularly in rat model studies.[5]
From: Ancient Science of Life
(1) Gastric ulcers that develop in experimental settings as a result of administering aspirin to test subjects, modeling the effects of NSAIDs on the gastric system.[6] (2) Ulcers created in experimental rats as a result of administering aspirin, used to test the efficacy of the plant extracts.[7] (3) Ulcers that are caused by the administration of aspirin, a focus of the study in evaluating anti-ulcer activity.[8]
From: Journal of Ayurveda and Integrative Medicine
(1) A type of gastric ulcer that occurs as a side effect of aspirin, a common non-steroidal anti-inflammatory drug.[9]