Significance of Apoptosis

Apoptosis is a vital process of programmed cell death essential for maintaining cellular homeostasis and eliminating unhealthy cells. It plays a significant role in cancer therapies, as many treatments aim to induce apoptosis in cancer cells while preserving normal cells. The p53 gene, various pharmacological agents, and natural products can trigger this process, which is characterized by specific cellular changes like DNA fragmentation. Understanding apoptosis is crucial for developing effective strategies in cancer treatment and addressing other diseases linked to cellular degeneration.

Synonyms: Programmed cell death, Cell death, Self-destruction, Cell suicide, Cellular self-destruction

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

The concept of Apoptosis in scientific sources

Science Books

Apoptosis is programmed cell death influenced by bioactive compounds in Siddha spices, and it can also be induced in cancer cells by specific compounds, highlighting its significance in health and disease management.

Significance in Scientific journals, articles, etc.:

From: The Malaysian Journal of Medical Sciences

(1) This term refers to programmed cell death and is discussed in the context of malaria and how the disease may trigger this cellular process.[1] (2) This is programmed cell death, which is one of the cellular functions influenced by the p53 gene.[2] (3) This is a natural cellular process, also known as programmed cell death, which is a response of the cells to various stimuli, and it can be induced by certain viruses.[3] (4) This is a programmed cell death, and VP3 induces apoptosis in various human transformed and/or tumorigenic cell lines, and the rate of VP3-induced apoptosis is variable in one tumor cell line to another, and VP3 aggregates and the cellular DNA condenses and/or is fragmented.[4] (5) Apoptosis is programmed cell death, and IGF1R activation contributes to the inhibition of apoptosis, anchorage-independent growth, and tumour-associated inflammation.[5]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.