Significance of Anticancer agent
Anticancer agents are substances designed to combat cancer. According to Ayurveda, these agents are being investigated for their ability to combat the disease, such as coixnolides. Science highlights that these are substances used to treat cancer, like paclitaxel, Borrelidin, and those found in Aloe vera. Health Sciences defines anticancer agents as compounds that inhibit cancer cell growth or progression, including substances from plants and other sources, such as imidazothiazole derivatives, ginger, and NDV.
Synonyms: Anticancer drug, Chemotherapeutic agent, Tumor inhibitor, Cancer treatment, Cancer therapy, Anti-tumor agent, Chemotherapy drug
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Anticancer agent'
In Hinduism, an anticancer agent is a substance studied for its cancer-fighting abilities. This includes substances like quinones, as well as drugs like 5-FU and platinum analogues, which display time-dependent effects. Coixnolides in Gavedhuka seeds are also seen as having anticancer properties.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Anticancer agents, such as 5-FU, methotrexate, 6- mercaptopurine, and platinum analogues, demonstrate time-dependent variations in their pharmacokinetics, crucial for chronotherapeutic applications.[1] (2) These are substances that are being investigated for their ability to combat the disease, as referenced in the context of quinones.[2]
From: International Research Journal of Ayurveda and Yoga
(1) An anticancer agent is a substance that can combat cancer, a property attributed to coixnolides found in Gavedhuka seeds.[3]
The concept of Anticancer agent in scientific sources
Anticancer agents are substances used to treat or prevent cancer. They work by various mechanisms, including inhibiting cell growth, promoting cell death, and targeting cancerous cells. These agents encompass drugs, compounds, and substances derived from natural sources, like plants and marine organisms.
From: International Journal of Pharmacology
(1) It refers to the capabilities of the novel minocycline/zinc complex to inhibit the proliferation and viability of large lung cancer cells, specifically H 460 cells.[4] (2) L-canavanine, is naturally abundant in alfalfa, Medicago sativa (L.), suggesting a potential source for cancer treatment compounds.[5] (3) Anticancer agents are substances that can prevent or inhibit the growth of cancer cells, and this study aims to explore the possible application of glucosinolates as anticancer agents.[6] (4) Zerumbone is a food phytochemical that has a distinct potential for use as an effective anti-leukemic as well as this.[7] (5) This study provided evidence that Sulforaphane could be a potent one in myeloid leukemia cells, due to its effects on cell proliferation.[8]
From: Asian Journal of Pharmaceutics
(1) One type of drug that can be delivered using chitosan microparticles or nanoparticles for controlled release.[9] (2) Polymeric micelles have a broad area of application, such as delivery of these to treat tumors, among other uses.[10] (3) These are agents such as EGFR that are the first identified target to develop the novel anticancer agents.[11] (4) Retinoids can be used as preventive and therapeutic agents in this context.[12] (5) Doxorubicin is a potent one, widely used for cancer treatment, belonging to the anthracycline family.[13]
From: The Malaysian Journal of Medical Sciences
(1) These agents have been designed to take advantage of NQO1 because this enzyme is expressed at high levels in many human solid tumors and the hypoxic environment present in solid tumors would favor reductive metabolism.[14] (2) A potential treatment approach involving the use of NDV to treat cancer through virotherapy, specifically targeting cancer cells.[15]
From: Journal of Public Health in Africa
(1) These are substances or compounds that are used to treat or prevent cancer, with the aim of discovering new agents with higher effectivity and selectivity.[16]
From: International Journal of Pharmacology
(1) A substance that can effectively treat cancer, often by inhibiting cancer cell growth or inducing cell death.[17] (2) Taxane-class compounds, such as paclitaxel, represent a significant group of these agents that are crucial in the therapeutic treatment of various cancers.[18] (3) This is a substance that is used to treat cancer, either by killing cancer cells or slowing their growth.[19] (4) Novel substances sought for achieving more effective and rational cancer therapy, often found among natural products with anti-carcinogenic activities.[20] (5) This is a substance that is effective in combating cancer, such as Borrelidin, which has shown promise and is derived from Streptomyces species.[21]
From: Sustainability Journal (MDPI)
(1) A Thermo Stable Laccase from a Novel Bacillus sp. MSK-01 has the potential to be used as an Anticancer Agent, suggesting a possible medical application.[22] (2) Polyphenols are these agents but have toxicological concern to healthy cells.[23]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Anticancer agents are mentioned as being cytotoxic in nature, with severe side effects and limited efficacy, leading to the suggestion of chemoprevention as an attractive approach to prevent and cure cancer.[24]