Significance of Adverse reaction
Adverse reactions, as defined across various fields, consistently refer to undesirable or harmful effects resulting from medical treatments, medications, or substances. These reactions encompass a spectrum of effects, ranging from mild side effects to severe complications. They can stem from factors like improper use, allergic responses, or unintended consequences of treatment. Monitoring and understanding adverse reactions are crucial for assessing safety, guiding treatment decisions, and preventing potential harm to patients.
Synonyms: Side effect, Negative response, Unfavorable reaction, Harmful effect, Adverse effect, Negative effect, Unfavorable outcome
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Adverse reaction'
In Hinduism, "Adverse reaction" denotes negative health impacts from treatments or substances. It can include unintended side effects, discomfort, or harmful responses, highlighting the importance of safety and proper usage of medications or treatments to prevent these adverse effects.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Excess use of pseudo drugs, which results in higher incidence of adverse reaction, has motivated humans to return to nature for safer treatment or remedies.[1] (2) It refers to the negative effects experienced by the patient from allopathic medications, which prompted them to discontinue the treatment and seek alternative therapies.[2] (3) These are undesirable effects from medications, such as allopurinol and febuxostat, ranging from mild skin rashes to severe hypersensitivity reactions, leading to treatment discontinuation.[3] (4) These are severe negative effects that can result from the improper use of Vatsanabha, especially when not following guidelines.[4] (5) This refers to the negative effects that can occur as a result of anti-venom therapy, which can include reactions such as anaphylactic reactions and serum sickness.[5]
From: International Research Journal of Ayurveda and Yoga
(1) The formulation katphaladi yoga is proved to be used as a safe drug in Pediatric practice without any adverse reactions.[6] (2) In some studies the dose related effects / safety of Chandraprabha Vati were reviewed and it was found that there were no serious of these or toxicity symptoms.[7] (3) If study participants have this reaction, the medication will be stopped. The assessment will be carried out by the Common Terminology Criteria for Adverse Events (CTCAE) v 5.0 at each follow-up.[8] (4) The synthetic cosmetics can cause various and therefore, various herbal/Herbo mineral cosmetic preparations are needed to be standardized.[9] (5) None was observed during treatment with Sarjarasa Malahara Lepa ( Sarjarasa Ointment).[10]
From: Journal of Ayurvedic and Herbal Medicine
(1) None were observed by the clinician during the current study, as indicated in the text.[11] (2) This is the side effects of the treatments, and the text mentions that no adverse reactions found during the course of treatments.[12] (3) This refers to the negative side effects experienced by the children who took the specific formulation, which was monitored during the study to assess its safety.[13] (4) This refers to any unintended and undesirable effects that may occur as a result of taking a medication or undergoing a treatment.[14]
The concept of Adverse reaction in local and regional sources
Adverse reaction, as defined by regional sources, signifies the unintended negative consequences stemming from the use of a pharmaceutical product. These adverse effects are undesirable outcomes that may arise after taking medication.
From: Triveni Journal
(1) Unintended negative effects that may occur as a result of using a pharmaceutical product.[15]
The concept of Adverse reaction in scientific sources
Adverse reaction encompasses various unwanted or harmful effects from treatments, drugs, or medical practices. These can range from mild side effects to severe complications, impacting patient willingness, health, and study outcomes. Examples include effects from self-medication, specific drug treatments, and reactions in clinical trials.
From: International Journal of Pharmacology
(1) These are reactions occurring during the treatment period, including nausea and vomiting, anemia, proteinuria, and decreased white blood cell count.[16] (2) The occurrence of anesthetic reactions such as chills, nausea, bradycardia, and hypotension were compared.[17] (3) These are important factors in securing patient compliance with therapy, a major determinant of treatment success.[18] (4) Clinical signs or untoward reactions that were monitored after each injection of Doramectin.[19] (5) These include aggravation of restless legs, insomnia, postural hypotension, and hallucinations, and may occur during medicine treatment for primary restless legs syndrome.[20]
From: Asian Journal of Pharmaceutics
(1) CS NPs can be administered orally without the need for invasive or uncomfortable methods because they can improve drug absorption and lessen these effects.[21] (2) Harmful or unwanted effects caused by a medication or treatment.[22] (3) The consequences of food-drug interactions are serious, ranging from treatment failure to severe ones.[23] (4) Telepharmacy enhances clinical safety, improves therapeutic outcomes, and expands access to pharmaceutical services by minimizing adverse reactions.[24] (5) These are recognized hazards of drug therapy and a main cause for mortality and morbidity.[25]
From: The Malaysian Journal of Medical Sciences
(1) Some authors believe that antibiotics are a health hazard for central venous catheter patients because of these issues and the non-oral origin of pathogens.[26] (2) Other than this, it also causes a reduction in L-asparaginase drug efficacy, leading to poor overall disease outcomes in paediatric acute lymphoblastic leukaemia patients.[27] (3) Unwanted effects that may develop immediately or after few hours due to respiratory distress, such as vasovagal episode or anaphylaxis reaction.[28] (4) This term refers to negative or undesirable medical events that occur after a medical intervention such as a vaccination, and these events can vary in severity and nature.[29] (5) These are undesirable effects that can occur from medical treatments, and the text mentions that serious ones associated with IVIG include hyper-viscosity syndrome and acute renal failure.[30]
From: South African Family Practice
(1) Adverse reactions to previous yellow fever vaccines should be obtained and if the vaccine is really indicated, it should be given in small incremental dosages under close supervision of an experienced team.[31] (2) Unfavorable responses to medical treatments, and the article explores the family history of these, particularly to anaesthetics, to assess risks.[32] (3) The undesirable effects that individuals may experience as a result of taking their medication, and they can impact adherence to treatment if they are severe or bothersome.[33] (4) Incidents that significantly affect how medical professionals make decisions in similar situations, possibly disproportionately, but psychologically difficult to overcome.[34] (5) Ivabradine is not associated with the typical adverse reactions associated with the β-blockers or other antianginal drugs, because of its exclusive chronotropic effect.[35]
From: Journal of Public Health in Africa
(1) The text mentions an increase in reported cases of these reactions to disinfectants, which were reported to poison control centers during the pandemic.[36] (2) These are unintended and harmful effects caused by a medication, and the fixed-dose combination products are not without risk, as they can cause adverse reactions, which emphasizes the importance of evidence-based medicine.[37] (3) In addition, the detection and reporting of adverse reactions associated with the COVID-19 vaccine in the early days of its administration and the shortened development period potentially affected vaccine uptake globally, especially among HCWs.[38] (4) Adverse reactions are experienced by children after ACTs administration and were already known and listed in package inserts, confirming the safety and tolerance of the medications.[39] (5) Negative experiences of donors which include donors being deferred or experiencing an adverse reaction occur in 11-57% of donors, and these might upset and reduce donor satisfaction and impact the blood donor return rate and decrease donor retention.[40]
From: African Journal of Primary Health Care and Family Medicine
(1) Adverse reactions are harmful effects that medicines may cause to patients, which is a major concern in the healthcare field, as they can lead to various complications.[41] (2) This refers to any harmful or unintended effect of a medication, which is a significant focus of the study on medication safety.[42] (3) Adverse reactions can be managed by providing opportunities within the health system to deliver cost effective services, and by providing opportunities for managing drug interactions.[43] (4) These are the negative physical responses that occur in people with the alpha-gal allergy after consuming mammalian meat, ranging from mild symptoms to severe anaphylaxis.[44]
From: Onderstepoort Journal of Veterinary Research
(1) These were not observed in the treatment group, suggesting the safety of ivermectin via subcutaneous route.[45] (2) Serovar B did not induce any adverse reactions, which is an important finding in the study.[46]
From: South African Journal of Physiotherapy
(1) Negative effects experienced by patients during or after the intervention, which influenced the specific techniques used in the neurodynamic mobilization.[47]
From: Journal of Metabolic Health
(1) This is an unwanted or harmful effect that occurs after taking a medication or receiving a vaccine.[48]
From: South African Journal of HIV Medicine
(1) These are harmful effects caused by a medical treatment, as the text describes.[49]
From: Journal of Medicinal Plants for Economic Development
(1) They are an issue relating to the growing use of herbal medicines, requiring safety monitoring.[50]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) It is a criteria for exclusion in the study, in order to prevent any complications or harm to the participants.[51] (2) These to intravenous immunoglobulins can be local or systemic, with systemic ones including immediate, delayed, or late manifestations, such as headache, nausea, and renal impairment.[52] (3) Adverse reactions became a focal point, with some tweets emphasizing potential or rare negative consequences, influencing vaccine hesitancy and contributing to a cautious approach towards vaccination.[53] (4) The downsides of industry-funded clinical trials mainly include conflict of interest, methodological bias, reporting bias, publication bias, selecting an inappropriate comparator, and the concealment of adverse reactions.[54] (5) An adverse reaction is an unwanted or harmful effect resulting from exposure to a substance or condition, and no adverse reaction was observed following exposure to different levels of both the signals.[55]
From: International Journal of Pharmacology
(1) Unfavorable effects experienced by patients during treatment, which in meta-analyses comparing roxadustat to control groups for renal anemia were found to be not statistically meaningful.[56] (2) Negative consequences of drug administration, which for cholic acid and its preparations, can be associated with their surfactant properties and include sedation or even death.[57] (3) These may be caused by the relative increases of components in the whole body after long-term administration of Epimedium.[58] (4) Undesirable responses that can occur despite methotrexate generally being considered safe and easy to use.[59] (5) The treatment combination of doxofylline and budesonide shows few adverse reactions.[60]
From: South African Journal of Psychiatry
(1) Reasons for discontinuation of treatment due to these in child and adolescent clinical trials included: Aggression, Irritability, Somnolence and Vomiting[61] (2) These were reported with dolutegravir, including mild to moderate nausea, diarrhea, and dizziness, with neuropsychiatric effects occurring less frequently than with efavirenz.[62] (3) These are negative effects that occur after taking a medication, and the study aimed to improve the documentation of these reactions.[63]
From: Religions Journal (MDPI)
(1) Clients may not disclose their ADCs because they have met with these upon sharing their encounters with mental health professionals in the past.[64]